Protein Alignment dpy and rtn1a

DIOPT Version :10

• Sequence 1: NP_001260032.1
• Gene: dpy / 318824
• FlyBaseID: FBgn0053196
• Length: 22949
• Species: Drosophila melanogaster
• Sequence 2: NP_001025138.2
• Gene: rtn1a / 323706
• ZFINID: ZDB-GENE-030131-2426
• Length: 818
• Species: Danio rerio
• Alignment Length: 801
• Identity: 165/801 - (20%)
• Similarity: 267/801 - (33%)
• Gaps: 247/801 - (30%)

  Fly  4614 ETTTNVPIGSTG---GQVTGQTTAPPSEFR----TTIRVEESTLPSRSTD---RTTPSESPETPT 4668
            |...|...||.|   .::.....||..:|.    |.:.:|.::.....:|   :::|.|.....:
Zfish    19 EEEKNGMFGSAGPHFDEMRDDLRAPKQQFHPFEGTGVAMETASTGDSLSDMFMKSSPVEGDLYTS 83

  Fly  4669 ILPSDSTTRTYSDQ----TTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTNVPIGSTGGQ 4729
            :|.|.|::..::|.    ::|..|          |.|:|             |.|:..||.|.|
Zfish    84 LLSSKSSSNPFNDGASLFSSEGNR----------SPPAP-------------TGTDSGIGMTPG- 124

  Fly  4730 VTEQTTSSPSEVRTTIR-------------------------VEESTLPSRS--ADRTTPSESPE 4767
                   .||:.:||::                         .:....|..|  .|.....:..|
Zfish   125 -------DPSDHQTTLQGSHKSDHYSYMDMGGDLCDFGSMGNAKNKQQPPMSGYGDEEDEEDDDE 182

  Fly  4768 TPTTLPSDFITRPHSEKTTESTRDVPTTRPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQV 4832
            ....: .||..:.....:.||:.|     ||:.......|     |..:.:|......||.|||.
Zfish   183 DEDDI-QDFKPKIEERGSKESSHD-----PFDLGRYLEKS-----PLGSEDTEVKTSTGSAGGQH 236

  Fly  4833 TEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFITRPHSEKTTESTRDVPTT 4897
            .......||        :|.....||..|   .|:|::.:.:.....|..|| ..:|..|..|..
Zfish   237 AFPYVEDPS--------DEEMADFRSYRR---METPQSASPVKITVTTESHS-TASEPVRVSPQG 289

  Fly  4898 RPFEASTPSSASLETTVPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSTD 4962
            ...|..:..|.. :..:|:|||                    |.|         |:.:  :.|:.
Zfish   290 GMSERDSVLSFG-QQGLPTVTL--------------------SEP---------EDDS--AASSA 322

  Fly  4963 RTTPSESPETPTTLPSDFTTRPHSEQTTESTRDVPTTRPFEASTPSPASLETTVPSVTLETTTNV 5027
            ..:|:.|| |....|||....|...::..||:|..:.    :|.|:|..:.....|....:....
Zfish   323 NHSPNHSP-TGRESPSDVLFHPAGMKSMSSTQDSSSI----SSHPNPPPIHDIKTSAKPSSPWAQ 382

  Fly  5028 PIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTTLPSDFITRTYSDQTT 5092
            .:..:|.:      |..||:.......:|.|...:: :|.|::...:||:.|  |...:|:..|.
Zfish   383 DLQGSGDE------SGDSEIEQVAEELDSPLHDLTS-KTPPAKGGFSPTSNP--FEPPSYTSATD 438

  Fly  5093 ESTR--DVPTTRPFEASTPSPASLETTVPSVTSETTTNVPIGSTGGQVTGQTTAPPSEFRTTIRV 5155
            :::.  |.|.|....||.|...|                 .||..|  .||::.||  ..:.:|.
Zfish   439 KASNPFDKPQTNKVSASNPFDLS-----------------AGSKMG--FGQSSNPP--LYSLLRE 482

  Fly  5156 E-ESTLPSRSTDRTTPSESPETPTTLPSDFTTRPHSDQTTESTRDVPTTRPFEASTPSPASLETT 5219
            | |:.|.|   |....|.|.|:|                         .|..|.|.|.|.  |.:
Zfish   483 EREAELDS---DLLIESASEESP-------------------------KREQEYSAPKPP--EPS 517

  Fly  5220 VPSVTLETTTNVPIGSTGGQVTEQTTSSPSEVRTTIRVEESTLPSRSADRTTPSESPETPTLPSD 5284
            .|.:| :..::.||          ||||.|                    ::|...|...:...:
Zfish   518 SPLIT-DNMSSKPI----------TTSSVS--------------------SSPFTEPRVVSAQKE 551

  Fly  5285 FTTRPHSEQTTESTRDVPATRPFEASTPSPASLETTVPSVTSEATTNVPIGSTGGQVTEQTTSSP 5349
                |..|:..|..:..|..:|    .|.|....:|.|......|:.|    |..:...|.|.|.
Zfish   552 ----PEKEKEKEKEKAAPIEKP----KPQPEDSWSTKPRPAVMGTSTV----TPEKQPSQETESK 604

  Fly  5350 SEVRTTIRVEESTLPSRSTDR 5370
            |         :|::.|.||::
Zfish   605 S---------KSSIVSSSTEK 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dpy	NP_001260032.1	EGF_3	137..166	CDD:463759
		EGF_CA	212..247	CDD:238011
		EGF_CA	255..>286	CDD:214542
		EGF_CA	298..331	CDD:238011
		EGF_CA	338..373	CDD:238011
		EGF_CA	413..456	CDD:238011
		EGF_CA	457..490	CDD:238011
		EGF_CA	497..>529	CDD:214542
		EGF_CA	580..>612	CDD:214542
		EGF_3	676..702	CDD:463759
		EGF_CA	1022..1056	CDD:214542
		EGF_CA	2227..2260	CDD:238011
		EGF_CA	2393..>2422	CDD:214542
		Herpes_BLLF1	<4032..4489	CDD:282904
		Herpes_BLLF1	<4334..4797	CDD:282904	41/223 (18%)
		PHA03255	4845..>5021	CDD:165513	37/175 (21%)
		DUF5585	4959..5356	CDD:465521	87/399 (22%)
		PHA03247	<5170..5799	CDD:223021	41/201 (20%)
		PRK12495	<5749..5877	CDD:183558
		PHA03247	<5865..6485	CDD:223021
		Chi1	6385..>6609	CDD:442692
		Herpes_BLLF1	<6607..7102	CDD:282904
		Herpes_BLLF1	<7027..7490	CDD:282904
		DUF5585	7550..7954	CDD:465521
		DUF5585	7881..>8130	CDD:465521
		Atrophin-1	18652..>19081	CDD:460830
		PHA03247	<18873..19514	CDD:223021
		ZP	22576..22811	CDD:214579
rtn1a	NP_001025138.2	PHA03307	231..>457	CDD:223039	62/283 (22%)
		Reticulon	632..796	CDD:460562