Protein Alignment CG31321 and SLC46A2

DIOPT Version :10

• Sequence 1: NP_731899.1
• Gene: CG31321 / 318681
• FlyBaseID: FBgn0051321
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_149040.3
• Gene: SLC46A2 / 57864
• HGNCID: 16055
• Length: 475
• Species: Homo sapiens
• Alignment Length: 440
• Identity: 89/440 - (20%)
• Similarity: 181/440 - (41%)
• Gaps: 80/440 - (18%)

  Fly   144 IFPLIVLL------FAGGW-ADRYNKRKPCMIMPIIGEALSFTCQIISSIFFESLPMEFGAYCEA 201
            |:.|:|.|      :..|| :|||: ||..:.|.::|..||....::..:....:.:.:||   |
Human    80 IYNLVVGLSPLLSAYGLGWLSDRYH-RKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGA---A 140

  Fly   202 IVPALFGGLTFCLMAIYSYITIATPEEDRVFRFGIFAMFVTGVPFIGQPISGVLFTTL-GYTWSF 265
            .:..||||.:.....:.:..::.:.|..|..|..:..:.:....|.|...||.||..: |::
Human   141 ALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLMLGLAGFCGSMASGHLFKQMAGHS--- 202

  Fly   266 ASAIVFQLIAI----FYIIFFIKEVKTTPTTSTTANEPPPLPTSLPPKQQGADNMAYETTNLDEL 326
            ...::....::    |.:::.:..:|...:.:..:.|.|.:.|     ..|... .|.|.:.|:|
Human   203 GQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDT-----VSGTVG-TYRTLDPDQL 261

  Fly   327 QGNKNVNFQLTPQMEPKVEVVPPKRSLLKELFDPTLVLDCIRFPLVKRPNNGRMLLILLLCAYFL 391
            .....|....:|..      ..|.::.:..||...::.|               |.::
Human   262 DQQYAVGHPPSPGK------AKPHKTTIALLFVGAIIYD---------------LAVV------- 298

  Fly   392 TVGPTSGENDYWYRFTLKK-LAWN--------GNDFSIYLTLSSGAALVGTFIGTAILSKLLKVS 447
                  |..|....|.|:: |.||        ...::|::|         :|:|..:.|:..:
Human   299 ------GTVDVIPLFVLREPLGWNQVQVGYGMAAGYTIFIT---------SFLGVLVFSRCFR-- 346

  Fly   448 DSMIGMLSALSIVCSRVLFAFSSSTASFYVAGVVDMFVSLRVIAIKTIGSSIVAGDELSKMYSIF 512
            |:.:.|:..:|.....:|.||...|..||:|..|.:|..:.|..|::..|.::.|....|::.|.
Human   347 DTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVIL 411

  Fly   513 GISEPIAQFIFPPIFSEIYKSTVDSFPGAIW-LFGEIFYIPNVLVFVVCY 561
            .:|..:...:...::::||:.|:|.|.|:.: |...:.::..:.:.:|.|
Human   412 QLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIVAY 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31321	NP_731899.1	MFS_SLC46	36..561	CDD:340944	88/438 (20%)
SLC46A2	NP_149040.3	MFS_SLC46A2_TSCOT	19..460	CDD:341008	87/437 (20%)