DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31321 and CG17637

DIOPT Version :9

Sequence 1:	NP_731899.1	Gene:	CG31321 / 318681	FlyBaseID:	FBgn0051321	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_649237.1	Gene:	CG17637 / 40275	FlyBaseID:	FBgn0037004	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	502	Identity:	90/502 - (17%)
Similarity:	173/502 - (34%)	Gaps:	114/502 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 QILAAD--VSGKRAPMAAIFPLIVLLFAGGWADRYNKRKPCMIMPIIGEALSFTCQIISSIFFES 190
            ::|..|  |.|.|    .|...:.....|..:| ::.||..|::.:..........::.|.:|.:
  Fly    57 RVLLVDGLVYGVR----GILGFVTTPVMGAISD-FHGRKVVMLLAVATTYAPIPFMMLKSWWFFA 116

  Fly   191 LPMEFGAYCEAIVPALFGGLTFCLMAIYSYITIATPEEDRVFRFG-IFAMFVTGVPFIGQPISGV 254
            : :...:.|         |.|:  .:..:|:...|..|:|...:| :.|.|..|:.| ...:...
  Fly   117 I-LTVSSIC---------GSTY--SSSLAYVADTTTVENRSKGYGFVAASFGAGIAF-SPSLGNY 168

  Fly   255 LFTTLGYTWSFASAIVFQLIAIFYIIFFIKEVKTTPTTSTTANEPPPLPTSLPPKQQGADNMAYE 319
            |..:.|.......|.:..:|.|.:|||.:.|...........||             ..||.. |
  Fly   169 LMKSYGSASVILIATITGMINILFIIFAVPESLVLKEKKVILNE-------------NNDNKV-E 219

  Fly   320 TTNLDE---------LQGNKNVNFQLTPQMEPKVEVVPPKRSL---------------LKELFDP 360
            .|.:|:         |.|...||.::.   :|..:.:...:.|               .||..|.
  Fly   220 DTKVDDISPKEKKENLNGEGKVNVEVN---KPTSQNIVTNKELDQQFSKEENLQNDLTEKEKIDN 281

  Fly   361 TLVLDCIRFPLVKRPNNGRMLLILLLCAYFLTVGPTSGENDYWYRFTLKKLAWNGNDFSIYLTLS 425
            ..:.....:.::::....:.||::.|.. ||::.|.:|.:               :...:||..:
  Fly   282 GSLNSSDLWEVLRKSRKDKNLLVIYLIT-FLSIWPFAGVD---------------STAPVYLKTN 330

  Fly   426 SGAALVGTFIGTAILSKLLKVSDSMIG------------MLSALSIVCSRVLFAFSSSTASFYVA 478
            .|.......:...:||.|...|:.::|            .|..|.:....:.|.|.:....::::
  Fly   331 MGFEYEEVSMMLGLLSVLAITSNILLGYIMNIVGAKWSIRLGLLLLFLQMLFFGFGTHHWMYWLS 395

  Fly   479 GVVDMFVSLRVIAIKTIGSSIVAGDELSKMYSIFGISEPIAQFIFPPIFSEIY-----KSTVD-- 536
            .::....::...|...:.|...:.|....:..|....|.:::.:.|..|..::     .|..|
  Fly   396 SILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGLLFFIFQDDSETDLK 460

  Fly   537 -----SFPGAIWLFGEIFYIPNVLVF---VVCYFLLRRRKANEEKSV 575
                 |.|         |.|..:.||   |:..|:.:....|||..|
  Fly   461 VNSPISMP---------FVISAISVFVAIVLSSFIKKDTLGNEETRV 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31321	NP_731899.1	MFS	141..>271	CDD:119392	23/130 (18%)
		MFS_1	143..>271	CDD:284993	23/128 (18%)
		MFS	<379..559	CDD:119392	34/206 (17%)
CG17637	NP_649237.1	MFS	25..487	CDD:119392	86/489 (18%)
CG17637	NP_649237.1	MFS_1	30..441	CDD:284993	74/434 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810