DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31321 and CG18281

DIOPT Version :9

Sequence 1:	NP_731899.1	Gene:	CG31321 / 318681	FlyBaseID:	FBgn0051321	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_649236.1	Gene:	CG18281 / 40274	FlyBaseID:	FBgn0037003	Length:	542	Species:	Drosophila melanogaster

Alignment Length:	523	Identity:	96/523 - (18%)
Similarity:	184/523 - (35%)	Gaps:	124/523 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 QILAAD--VSGKRAPMAAIFPLIVLLFAGGWADRYNKRKPCMIMPIIGEALSFTCQIISSIFFES 190
            ::|..|  |.|.|    .|...:.....|..:| ::.||..|::.:..........::.|.:|.:
  Fly    57 RVLLVDGLVYGVR----GILGFVTTPVMGAISD-FHGRKVVMLLAVATTYAPIPFMMLKSWWFFA 116

  Fly   191 LPMEFGAYCEAIVPALFGGLTFCLMAIYSYITIATPEEDRVFRFGIF-AMFVTGVPFIGQPISGV 254
            : :...:.|         |.|:  .:..:|:...|..|:|...:||. |.|..|:.| ...:...
  Fly   117 I-LTVSSIC---------GSTY--SSSLAYVADTTTVENRSKGYGIVAASFGAGIAF-SPSLGNY 168

  Fly   255 LFTTLGYTWSFASAIVFQLIAIFYIIFFIKEVKTTPTTSTTANEPPP-LPTSLPPKQQ------- 311
            |..:.|.......|.:..||.|.:|||.:.|.......:...:|... ....:.||::
  Fly   169 LMKSYGSASVILIAAITGLINIMFIIFAVPESLVLKEKNNMLDEESDNKMEDINPKERKEILNRE 233

  Fly   312 -------GADNMAYETT-NL---DEL--QGNKNVNFQ--LTPQMEPKVEVVPPKRSLLKELFDPT 361
                   .|:...:.|: ||   .||  |.||..|.|  ||.                ||..|..
  Fly   234 EKLNNHVSANKSNHGTSQNLVTNKELGQQFNKEENLQNDLTE----------------KEKIDNG 282

  Fly   362 LVLDCIRFPLVKRPNNGRMLLILLLCAYFLTVGPTSGENDYWYRFTLKKLAWNGNDFSIYLTLSS 426
            .:.....:.::::....:.||::.|.. ||::.|.:|.:               :...:||..:.
  Fly   283 SLNSSDLWEVLRKSRKDKNLLVIYLIT-FLSIWPFAGVD---------------STAPVYLKTNM 331

  Fly   427 GAALVGTFIGTAILSKLLKVSDSMIG------------MLSALSIVCSRVLFAFSSSTASFYVAG 479
            |.......:...:||.|...|:.::|            .|..|.::.....|.|.:....::::.
  Fly   332 GFEYEEVSMMLGLLSVLAITSNLLLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTHHWMYWLSS 396

  Fly   480 VVDMFVSLRVIAIKTIGSSIVAGDELSKMYSIFGISEPIAQFIFPPIFSEIY-------KSTVD- 536
            ::....::...|...:.|...:.|....:..|....|.:::.:.|..|..::       |:.|:
  Fly   397 ILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQDDSKNKVNS 461

  Fly   537 --SFPGAIWLFGEIFYIPNVLVFVVCYFLLRRR-------------KANEE------KSVVEMEQ 580
              |.|..|...|       |.|.:|....:::.             .|:|:      |:..:.|:
  Fly   462 PISMPFVISAIG-------VFVAIVLTGFIKKETVEKAPLIYKIIDDASEDEVEPLAKTTFKYEK 519

  Fly   581 NGG 583
            |.|
  Fly   520 NNG 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31321	NP_731899.1	MFS	141..>271	CDD:119392	24/130 (18%)
		MFS_1	143..>271	CDD:284993	24/128 (19%)
		MFS	<379..559	CDD:119392	34/201 (17%)
CG18281	NP_649236.1	MFS	25..485	CDD:119392	90/484 (19%)
CG18281	NP_649236.1	MFS_1	30..441	CDD:284993	79/433 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810