Protein Alignment CG31321 and Slc46a3

DIOPT Version :10

• Sequence 1: NP_731899.1
• Gene: CG31321 / 318681
• FlyBaseID: FBgn0051321
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_001020139.1
• Gene: Slc46a3 / 288454
• RGDID: 1307594
• Length: 461
• Species: Rattus norvegicus
• Alignment Length: 481
• Identity: 107/481 - (22%)
• Similarity: 185/481 - (38%)
• Gaps: 117/481 - (24%)

  Fly   122 KAELEAQILAADVSGKRAPMAAIFPLIVLLFAGGWADRYNKRKPCMIMPIIGEALSFTCQIISSI 186
            ||.|.:  |..::||....:.:.|.|:      ..:|.:.::.| |::..:| :|.....:.:..
  Rat    68 KASLFS--LQVEISGLIPGLVSTFMLL------SSSDNHGRKLP-MVLSSLG-SLGTNLWLCAMS 122

  Fly   187 FFESLPMEFGAYCEAIVPALFGGLTFCLMAIYSYITIATPE-EDRVFRFGIFAMF---VTGVPFI 247
            :|: ||::. ......:.||||..|....|.::||.....| :.|:.|..:....   |||:..:
  Rat   123 YFD-LPLQL-LVASTFIGALFGNYTTFWGACFAYIVDQEKEYKHRIIRIAVLDFMLGVVTGLTGL 185

  Fly   248 GQPISGVLFTTLGYTWSFASAIVFQLIAIFYIIFFIKEVKTTPTTSTTANEPPPLPTSLPPKQQG 312
            .   ||.....||:.||:....|..|:.:.||:||:.:
  Rat   186 S---SGYFIRELGFAWSYFIIAVVVLVNLAYILFFLSD--------------------------- 220

  Fly   313 ADNMAYETTNLDELQGNKNVNFQLTPQMEPKVEVVPPKRS-LLKELFDPTLVL----DCIRFPLV 372
                                     |..|...::|....| .||:||..|.:|    .|.|..|:
  Rat   221 -------------------------PIKESSSQIVTMSCSESLKDLFYRTYMLFKNGSCKRRSLL 260

  Fly   373 KRPNNGRMLLILLLCAYFLTV-GPTSGENDYWYRFTLKK----LAWNGNDFSIYLTLSSGAAL-- 430
                   .|||..|..||..| |.|.       .|||.:    |.||    .:|  :..|:||
  Rat   261 -------CLLIFTLVVYFFVVFGITP-------VFTLYELGPPLCWN----EVY--IGYGSALGS 305

  Fly   431 ---VGTFIGTAILSKLLKVSDSMIGMLSALSIVCSRVLFAFSSSTASFYVAGVVDMFVSLRVIAI 492
               :.:|:|..:.|..||  |..|..:...:.:...:|.||:.:|...::..:...|..:.:..:
  Rat   306 LSFLSSFLGIWLFSYCLK--DIHIAYVGIFTTMVGMMLTAFTRTTLMMFLVRISFFFTIMPLSIL 368

  Fly   493 KTIGSSIVAGDELSKMYSIFGISEPIAQFIFPPIFSEIYKSTVDSFPGAIWLFGE-IFYIPNV-L 555
            :::.|.:|...|...:::.....|.:........::.||.:||..:||.::|... :..:|.| |
  Rat   369 RSMLSKVVHSTEQGVLFACIAFLETLGGVTSTSAYNGIYSATVAWYPGFVFLLSAGLLVLPAVSL 433

  Fly   556 VFVVC-------YFLLRRRKANEEKS 574
            ..|.|       |.||...:.:|..|
  Rat   434 CMVKCIGWEEGSYTLLIHDEPSEHTS 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31321	NP_731899.1	MFS_SLC46	36..561	CDD:340944	102/466 (22%)
Slc46a3	NP_001020139.1	MFS	3..437	CDD:475125	100/457 (22%)
		Tyrosine-based lysosomal-sorting motif. /evidence=ECO:0000250|UniProtKB:Q7Z3Q1	446..449		1/2 (50%)