Protein Alignment CG31321 and SLC46A1

DIOPT Version :10

• Sequence 1: NP_731899.1
• Gene: CG31321 / 318681
• FlyBaseID: FBgn0051321
• Length: 601
• Species: Drosophila melanogaster
• Sequence 2: NP_542400.2
• Gene: SLC46A1 / 113235
• HGNCID: 30521
• Length: 459
• Species: Homo sapiens
• Alignment Length: 423
• Identity: 85/423 - (20%)
• Similarity: 154/423 - (36%)
• Gaps: 91/423 - (21%)

  Fly   148 IVLLFA----GGWADRYNKRKPCMIMPIIGEALSFTCQIISSIFFESLPMEFGAY-CEAIVPAL- 206
            :|.||:    |.|:|... |:|.:::..:|..|    |.:.|:|...|.:..|.: ...|:.||
Human    95 LVGLFSSTLLGAWSDSVG-RRPLLVLASLGLLL----QALVSVFVVQLQLHVGYFVLGRILCALL 154

  Fly   207 --FGGLTFCLMAIYSYITIATPEEDRVFRFGIFAMFVTGVPFIGQPISGVLFTTLGYTWSFASAI 269
              ||||   |.|.::.:...:....|.||..:....:.....:...:.|......||...|..|:
Human   155 GDFGGL---LAASFASVADVSSSRSRTFRMALLEASIGVAGMLASLLGGHWLRAQGYANPFWLAL 216

  Fly   270 VFQLIAIFYIIFFIKEVKTTPTTSTTANEPPPLPTSLPPKQQGADNMAYETTNLDELQGNKNVNF 334
            ...:....|..|...|         |..||                   ::|.|...:.::::
Human   217 ALLIAMTLYAAFCFGE---------TLKEP-------------------KSTRLFTFRHHRSI-- 251

  Fly   335 QLTPQMEPKVEVVPPKRSLLKELFDPTLVLDCIRFPLVKRPNNGRMLLILLLCAYFLTVGPTSGE 399
                                            ::..:...|...|..|.|...|.|:.:....|.
Human   252 --------------------------------VQLYVAPAPEKSRKHLALYSLAIFVVITVHFGA 284

  Fly   400 NDYWYRFTLK-KLAWNGNDFSIYLTLSSGAALVGTFIGTAILS-KLLK--VSDSMIGMLSALSIV 460
            .|....:.|. .|.|:..      .:..|:|.......|::|: |||:  ::|:.:..:.....:
Human   285 QDILTLYELSTPLCWDSK------LIGYGSAAQHLPYLTSLLALKLLQYCLADAWVAEIGLAFNI 343

  Fly   461 CSRVLFAFSSSTASFYVAGVVDMFVSLRVI-AIKTIGSSIVAGDELSKMYSIFGISEPIAQFIFP 524
            ...|:|||::.|...: .|...:|:||.:. .|:...|.:|...|...::|.......:|.....
Human   344 LGMVVFAFATITPLMF-TGYGLLFLSLVITPVIRAKLSKLVRETEQGALFSAVACVNSLAMLTAS 407

  Fly   525 PIFSEIYKSTVDSFPGAIWLFGE-IFYIPNVLV 556
            .||:.:|.:|::...|..:|.|. :..||.||:
Human   408 GIFNSLYPATLNFMKGFPFLLGAGLLLIPAVLI 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31321	NP_731899.1	MFS_SLC46	36..561	CDD:340944	85/423 (20%)
SLC46A1	NP_542400.2	MFS_SLC46A1_PCFT	22..444	CDD:341007	85/423 (20%)