Protein Alignment CG31269 and ELANE

DIOPT Version :10

• Sequence 1: NP_001097818.1
• Gene: CG31269 / 318653
• FlyBaseID: FBgn0051269
• Length: 273
• Species: Drosophila melanogaster
• Sequence 2: NP_001963.1
• Gene: ELANE / 1991
• HGNCID: 3309
• Length: 267
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 82/279 - (29%)
• Similarity: 124/279 - (44%)
• Gaps: 50/279 - (17%)

  Fly     1 MSAVVLLILLGLSGLVSITAIRIKGNSTDGRFYKDQRIIGGQAAEDGFAPYQISLQGISGAHSCG 65
            ::.|:..:|||.:.|.|                   .|:||:.|.....|:.:||| :.|.|.||
Human    12 LACVLPALLLGGTALAS-------------------EIVGGRRARPHAWPFMVSLQ-LRGGHFCG 56

  Fly    66 GAIINETFVLTAAHCVENAFIPWLVVVTGTNKYN--QPGGRYFLKAIHIHCNYDNPEMHNDIALL 128
            ..:|...||::|||||.|..:..:.||.|.:..:  :|..:.|.........||...:.|||.:|
Human    57 ATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVIL 121

  Fly   129 ELVEPIAWDERTQPIPLPLVPMQPGDEV--ILTGWGSTVLWGTS---PIDLQVLYLQYVPHRECK 188
            :|......:...|...||....:.|:.|  :..|||   |.|.:   ...||.|.:..|...
Human   122 QLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWG---LLGRNRGIASVLQELNVTVVTSL--- 180

  Fly   189 ALLSNDEDCDVGHICTFSRLGE-GACHGDSGGPLVSNGYLVGL---VNWGWPCATGV-PDVHASV 248
                    |...::||..|..: |.|.||||.|||.||.:.|:   |..|  ||:|: ||..|.|
Human   181 --------CRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGG--CASGLYPDAFAPV 235

  Fly   249 YFYRDWIRNVM--SGNSKC 265
            ..:.:||.:::  |.::.|
Human   236 AQFVNWIDSIIQRSEDNPC 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31269	NP_001097818.1	Tryp_SPc	38..258	CDD:238113	74/231 (32%)
ELANE	NP_001963.1	Tryp_SPc	30..245	CDD:238113	74/231 (32%)