Protein Alignment Wsck and Src64B

DIOPT Version :10

• Sequence 1: NP_733018.1
• Gene: Wsck / 318600
• FlyBaseID: FBgn0046685
• Length: 791
• Species: Drosophila melanogaster
• Sequence 2: NP_001286937.1
• Gene: Src64B / 48973
• FlyBaseID: FBgn0262733
• Length: 553
• Species: Drosophila melanogaster
• Alignment Length: 552
• Identity: 128/552 - (23%)
• Similarity: 208/552 - (37%)
• Gaps: 151/552 - (27%)

  Fly   242 TTEVGLPSPVPAQPKIL-----SRTDRTVTIELSPIRNDNGPLSKLLVIVEYVDNALSQPFDAQL 301
            ||..|:|..|..:..:.     ||.:.    :||.::.|.         :|.:|:..|
  Fly    86 TTPTGVPGVVLKRVVVALYDYKSRDES----DLSFMKGDR---------MEVIDDTES------- 130

  Fly   302 LGSWQQ-----AQQDG-VPYYIAAELDYDRPED--------NRTRRFVVGDGKRYGRFTNKPLD- 351
              .|.:     .:|:| :|....||......||        ....:.::.:....|.|..:|.:
  Fly   131 --DWWRVVNLTTRQEGLIPLNFVAEERSVNSEDWFFENVLRKEADKLLLAEENPRGTFLVRPSEH 193

  Fly   352 QPDAHVHISLGLVSTLEGVTKTMYSRGTHDQH--VTSLDDFSY-----ATFEKGQSSVVALAVTC 409
            .|:.:   ||.:....:|       ||.|.:|  :..||:..|     .||...|:.|:|.:...
  Fly   194 NPNGY---SLSVKDWEDG-------RGYHVKHYRIKPLDNGGYYIATNQTFPSLQALVMAYSKEN 248

  Fly   410 VIFGSCLLLSLIAYFYLRYKTCRGRRLTGGNTHEMTLQTPIIERENNGYLVEDDPLPH----SPE 470
            .: |.|.:||         :.|                              ..|.|.    .||
  Fly   249 AL-GLCHILS---------RPC------------------------------PKPQPQMWDLGPE 273

  Fly   471 NFKQQLQQLVEGYERIPRNALRLNVNDVIGDGRFGEIITGKVSTNDFARDCTLHVLCLDDLNGT- 534
                    |.:.|| |||:.::|...  :|.|.|||:..||...:......||.       .||
  Fly   274 --------LRDKYE-IPRSEIQLLRK--LGRGNFGEVFYGKWRNSIDVAVKTLR-------EGTM 320

  Fly   535 TQAQLLRELRQLSQLKRQEHLLDFYGVSASPDWFYLIFEQQRMSLKRKLVESRLMAPSPRLTSLS 599
            :.|..|:|...:.:. |...|:..|.|.:..:..|::  |:.|| |..|::. |.....|.....
  Fly   321 STAAFLQEAAIMKKF-RHNRLVALYAVCSQEEPIYIV--QEYMS-KGSLLDF-LREGDGRYLHFE 380

  Fly   600 EQLVLQWIYELASAMNYLSSCQVVHRQLCSHSVFVTSDFKLKLSVFGPLPYMNIARQQPDHN--- 661
            :.:.:  ..::||.|.||.|.|::||.|.:.:|.:..:...|:..||      :||...|..
  Fly   381 DLIYI--ATQVASGMEYLESKQLIHRDLAARNVLIGENNVAKICDFG------LARVIADDEYCP 437

  Fly   662 --------RWLAPEVLRHQHHHSTRSDVWSLACVAWECCALGGTPYANAVASNQQLLEAIRAAVR 718
                    :|.|||.:.: ...|.:|||||...:..|....|..||..  ..:::::|.|....|
  Fly   438 KQGSRFPVKWTAPEAIIY-GKFSIKSDVWSYGILLMELFTYGQVPYPG--MHSREVIENIERGFR 499

  Fly   719 PAQPA--YVYGDLYQLLLNCWQLEPSERSSCE 748
            ..:|.  |...::|||||.||...|.:|.:.|
  Fly   500 MPKPTNHYFPDNIYQLLLQCWDAVPEKRPTFE 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wsck	NP_733018.1	WSC	42..115	CDD:460348
		fn3	130..222	CDD:394996
		PTKc	497..750	CDD:270623	72/266 (27%)
Src64B	NP_001286937.1	SH2_Src_family	158..259	CDD:199827	25/120 (21%)
		PTKc_Src_like	289..538	CDD:270630	72/268 (27%)
		SH3_Src_like	99..150	CDD:212779	12/72 (17%)