Protein Alignment Wsck and kin-21

DIOPT Version :10

• Sequence 1: NP_733018.1
• Gene: Wsck / 318600
• FlyBaseID: FBgn0046685
• Length: 791
• Species: Drosophila melanogaster
• Sequence 2: NP_501758.2
• Gene: kin-21 / 177826
• WormBaseID: WBGene00002204
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 292
• Identity: 62/292 - (21%)
• Similarity: 119/292 - (40%)
• Gaps: 46/292 - (15%)

  Fly   435 RLTGGNTHEMTLQTPIIERE---------NNGYL--VEDDPLPHSPENFKQQLQQLVEGYERIPR 488
            |.:.|.||:....|..:|.:         :.|:.  :..:..|..|....:.:.||::.:..:..
 Worm    95 RRSMGPTHKFLCITARVEDKYFHFQFNWNSEGWSCPILYEKFPRIPVKRYEHIYQLLDAWSLVVN 159

  Fly   489 NALRLN------------VNDVIGDGRFGEIITGKVSTNDFARDCTLHVLCLDDLNGTTQAQLLR 541
            ..:.::            :.:.:|.|.|||:|..|...........:.|..|  :....:.||:.
 Worm   160 QLVPISRCSMILQHSSIALENQLGRGAFGEVIKAKYVPMGATVPTEVAVKRL--IGDAKRPQLVD 222

  Fly   542 ELRQLSQLKRQEH--LLDFYGVSASPDWFYLIFEQQRMSLKRKLVESRLMAPSPRLTSLSEQLVL 604
            ...:.:.:...||  ::..||.::......|:.|.......||.::.....||.:        ::
 Worm   223 FCNEANIMTLLEHKNIVALYGFASLQQPIMLVIEFVPGGDLRKYLQRTPNVPSKQ--------II 279

  Fly   605 QWIYELASAMNYLSSCQVVHRQLCSHSVFVTSDFKLKLSVFG-----PLPYMNIARQQPDHNRWL 664
            ::..|:||.|.:|||..|:||.|.:.:..:|.:..:|:|.||     ....|...::.|  .|||
 Worm   280 KFAMEIASGMKHLSSKNVIHRDLAARNCLITKELNVKISDFGLSVNESETKMKSLKKAP--IRWL 342

  Fly   665 APEVLRHQHHHSTRSDVWSLACVAWEC---CA 693
            :||.. .:...:.::||||...:..|.   ||
 Worm   343 SPETF-SKGLFNEKTDVWSYGVLLTELMTRCA 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wsck	NP_733018.1	WSC	42..115	CDD:460348
		fn3	130..222	CDD:394996
		PTKc	497..750	CDD:270623	51/207 (25%)
kin-21	NP_501758.2	SH2	71..146	CDD:214585	9/50 (18%)
		PTKc	180..432	CDD:270623	51/207 (25%)