DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment su(r) and URA1

DIOPT Version :9

Sequence 1:	NP_727320.1	Gene:	su(r) / 31858	FlyBaseID:	FBgn0086450	Length:	1031	Species:	Drosophila melanogaster
Sequence 2:	NP_012706.1	Gene:	URA1 / 853664	SGDID:	S000001699	Length:	314	Species:	Saccharomyces cerevisiae

Alignment Length:	312	Identity:	73/312 - (23%)
Similarity:	134/312 - (42%)	Gaps:	38/312 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   537 FENPFGLASAPPTTSTAMIRRAFEQGWGFVVTKT-FGLDKDLVTNVSPRIVR---GTTSGYKYGP 597
            :||||..||.....:|..:........|..:||: ..|:::  .|..||.:.   |:.:.... |
Yeast    14 YENPFMNASGVHCMTTQELDELANSKAGAFITKSATTLERE--GNPEPRYISVPLGSINSMGL-P 75

  Fly   598 QQGCFLNIELISEKRAEYWLKSIGELKRDFPEKIVIASIMCSFNEEDWTELAIKAEQSGADAL-E 661
            .:|            .:|:|..:...::::|:...|...:...:.::...|..|.:.|..:.: |
Yeast    76 NEG------------IDYYLSYVLNRQKNYPDAPAIFFSVAGMSIDENLNLLRKIQDSEFNGITE 128

  Fly   662 LNLSCPHGMGERGMGLACGQDPELVEQISRWVRKAVKLPFFIKLTPNITDIVSIAAAAKRGGADG 726
            ||||||:..|:..:........|.:|::..:.:|    |..:||.|.. |.......||......
Yeast   129 LNLSCPNVPGKPQVAYDFDLTKETLEKVFAFFKK----PLGVKLPPYF-DFAHFDIMAKILNEFP 188

  Fly   727 GSAINTVQGL-MGLKADSTAWPAIGKEQ-----RTTYGGVSGNATRPMALKAISDIANRV-PGFP 784
            .:.:|::..: .||..|      :.||.     :..:||:.|...:|.||..:.....|: |...
Yeast   189 LAYVNSINSIGNGLFID------VEKESVVVKPKNGFGGIGGEYVKPTALANVRAFYTRLRPEIK 247

  Fly   785 ILGIGGIDSGEVALQFIHAGATVLQICSSVQNQDFTVIEDYCTALKALLYLK 836
            ::|.|||.||:.|.:.:..||::|||.:.:|.:...:.|.....||.::..|
Yeast   248 VIGTGGIKSGKDAFEHLLCGASMLQIGTELQKEGVKIFERIEKELKDIMEAK 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
su(r)	NP_727320.1	PRK11749	55..507	CDD:236967
		Fer4_20	58..170	CDD:291363
		NAD_binding_8	190..>234	CDD:290186
		PRK08318	527..1008	CDD:236237	73/312 (23%)
		DHPD_FMN	527..829	CDD:239244	70/303 (23%)
		Fer4_9	953..997	CDD:289930
URA1	NP_012706.1	PRK02506	4..314	CDD:235045	73/312 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342051
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1944
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100674
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.690