DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12056 and cyb5d2

DIOPT Version :9

Sequence 1:	NP_572535.1	Gene:	CG12056 / 31855	FlyBaseID:	FBgn0030099	Length:	287	Species:	Drosophila melanogaster
Sequence 2:	NP_001096144.1	Gene:	cyb5d2 / 795950	ZFINID:	ZDB-GENE-050506-83	Length:	267	Species:	Danio rerio

Alignment Length:	257	Identity:	95/257 - (36%)
Similarity:	129/257 - (50%)	Gaps:	26/257 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 TEIRQFLRRQTDNYLDQAGQDASIPLAFQAGDDIGTLFTPAELAKFNGEEEGRPLYLALLGSVFD 91
            |.:..:||::....      .||.|         |.|.|..:|:.:||.:..:.||||:||.|||
Zfish    32 TVLESWLRQRVSEV------SASSP---------GLLLTKEQLSLYNGGKNSKGLYLAILGQVFD 81

  Fly    92 VSRGIKHYGSGCSYNFFVGRDASVSFISGDFETYDPETADDVLTLKPDDLIGLAGWRDFYQKDYV 156
            |.:|.||||.|..|:||.|:|||.:||:|||.  :...::||.......::.|..|..|||:||.
Zfish    82 VEKGRKHYGPGGGYHFFTGKDASRAFITGDFT--EAGLSNDVSDFSESQIVALYDWLSFYQRDYT 144

  Fly   157 YKGRVIGRFYDEKGALTTYHHKFLELLEQARDAKRQVEELRARYPGCNIEWSEERGTRVWCTTTS 221
            ..|::|||||.|.|..|.........|......|.|.:.....||.||.||||..|.||||:|.|
Zfish   145 PVGKLIGRFYTETGQPTDALLHVEAFLSDGLKKKAQAQSEMQLYPSCNSEWSEASGGRVWCSTMS 209

  Fly   222 GDGKERSWIGYPRKLYSRGNKSFQCACVPDAELDEIDAGGKVAHGDAMLKPYDNCEPQAREC 283
            | |..|.|:|.||.|::.|:...:|.|        |.....|...:..|:.|.:|.|:|..|
Zfish   210 G-GIHRDWVGVPRMLFTPGSGHSRCVC--------IRLSDPVHSENRNLREYTDCPPRAESC 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12056	NP_572535.1	Cyt-b5	63..>117	CDD:278597	28/53 (53%)
cyb5d2	NP_001096144.1	Cyt-b5	55..124	CDD:278597	34/70 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581791
Domainoid	1	1.000	94	1.000	Domainoid score	I7450
eggNOG	1	0.900	-	-		E1_KOG1110
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H14701
Inparanoid	1	1.050	168	1.000	Inparanoid score	I4133
OMA	1	1.010	-	-		QHG59781
OrthoDB	1	1.010	-	-		D1355837at2759
OrthoFinder	1	1.000	-	-		FOG0006068
OrthoInspector	1	1.000	-	-		oto41724
orthoMCL	1	0.900	-	-		OOG6_104240
Panther	1	1.100	-	-	LDO	PTHR10281
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2676
SonicParanoid	1	1.000	-	-		X4364
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800