Protein Alignment CCT2 and Cct6a

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_033968.2
• Gene: Cct6a / 12466
• MGIID: 107943
• Length: 531
• Species: Mus musculus
• Alignment Length: 538
• Identity: 150/538 - (27%)
• Similarity: 286/538 - (53%)
• Gaps: 41/538 - (7%)

  Fly     8 VRVLKNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDGATILR 72
            |:.|..:|:..:|:.|...:...|..:.|::::.|||||..|:||:   .||.:::|.||..:|.
Mouse     4 VKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVS---GAGDIKLTKDGNVLLH 65

  Fly    73 AVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQATQVA 137
            .:.:.:|.|.::..::..||:..||||||..::..|||::|:..:.:.|||:||..|:..|.:.|
Mouse    66 EMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKA 130

  Fly   138 LEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGE---LKSI 199
            |:.|    :....|.|..|..|:::|||:|.:|:..:..|......||:::.::...|   |..:
Mouse   131 LQFL----EQVKVSKEMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIRKKDEPIDLFMV 191

  Fly   200 QIIKKSGGTLGDSFLDEGFLLDKKPGVHQP---QRIENARILIANTPMDTDKIKVFGSSIKVDSL 261
            :|::....:..|:.|..|.:||.  |...|   :|:|||.||..|..::.:|.:| .|.....|.
Mouse   192 EIMEMKHKSETDTSLIRGLVLDH--GARHPDMKKRVENAYILTCNVSLEYEKTEV-NSGFFYKSA 253

  Fly   262 AKIADLEMAEKEKMKEKVDKILKHK---CN------VFINRQLIYNYPEQLFADARVMSIEHADF 317
            .:...|..||::.::::|.||::.|   |.      |.||::.|..:.....|...::::..|..
Mouse   254 EEREKLVKAERKFIEDRVKKIIELKKKVCGDSDKGFVVINQKGIDPFSLDALAKEGIVALRRAKR 318

  Fly   318 DGIERLAYCTGGEIVSTFE--NPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEAC------TIV 374
            ..:|||....||..:::|:  ||..  ||..:::.:..:||:   :|:.:   |.|      |::
Mouse   319 RNMERLTLACGGIALNSFDDLNPDC--LGHAELVYEYTLGEE---KFTFI---EKCNNPRSVTLL 375

  Fly   375 IRGATQQILDEADRSLHDALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAF 439
            ::|..:..|.:...::.|.|..:...:.:..::.|.|..|..:|.|::|......|:..:.::||
Mouse   376 VKGPNKHTLTQIKDAIRDGLRAVKNAIDDGCVVPGAGAVEVALAEALIKYKPSVKGRAQLGVQAF 440

  Fly   440 ARALLSLPTAIADNAGYDSAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVL 504
            |.|||.:|..:|.|:|:|..:.:.:::|.|::..|.:|:|:..|:.....|:|:.:::.||:|:|
Mouse   441 ADALLIIPKVLAQNSGFDLQETLVKVQAEHSESGQLVGVDLSTGEPMVAAEMGVWDNYCVKKQLL 505

  Fly   505 MSASEAAEMILRVDNIIR 522
            .|.:..|..||.||.|:|
Mouse   506 HSCTVIATNILLVDEIMR 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	149/536 (28%)
Cct6a	NP_033968.2	chap_CCT_zeta	3..530	CDD:274088	150/538 (28%)