Protein Alignment CCT2 and CCT2

DIOPT Version :9

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_006422.1
• Gene: CCT2 / 10576
• HGNCID: 1615
• Length: 535
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 380/533 - (71%)
• Similarity: 453/533 - (84%)
• Gaps: 1/533 - (0%)

  Fly     3 MSLNPVRVLKNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDG 67
            :||.||.:.|..|.||:||.|||:|||||||||||||||||||||||||:::||:|. :.|||||
Human     4 LSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS-LMVTNDG 67

  Fly    68 ATILRAVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQ 132
            ||||:.:||||||||:|||||||||:|||||||||||||:|||||||.|:.:|:|||.|::|||:
Human    68 ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWRE 132

  Fly   133 ATQVALEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGELK 197
            ||:.|.|||.::|.|:.|.:.|||.||:|||.||||||:|..|||.|..|||:||:||||||.|:
Human   133 ATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLE 197

  Fly   198 SIQIIKKSGGTLGDSFLDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLA 262
            :|.||||.||:|.||:||||||||||.||:||:|||||:||||||.|||||||:|||.::|||.|
Human   198 AIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTA 262

  Fly   263 KIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCT 327
            |:|::|.||||||||||::||||..|.|||||||||||||||..|.||:||||||.|:||||..|
Human   263 KVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVT 327

  Fly   328 GGEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEACTIVIRGATQQILDEADRSLHD 392
            ||||.|||::|.|||||.|.:||:||||||.|:.||||.||||||||:|||||||||||:|||||
Human   328 GGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHD 392

  Fly   393 ALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYD 457
            ||||||.|||:||.::||||||.|||.||.:.|..||||||:|:|::|:||..|||.||||||||
Human   393 ALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYD 457

  Fly   458 SAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIR 522
            ||.||::|||.|::|..|.||||..|.:.|:..|||||||.||||||:||:||||:||||||||:
Human   458 SADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIK 522

  Fly   523 CAPRRRVPDRGYC 535
            .|||:||||...|
Human   523 AAPRKRVPDHHPC 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	PTZ00212	1..530	CDD:185514	376/526 (71%)
		TCP1_beta	10..527	CDD:239452	370/516 (72%)
CCT2	NP_006422.1	TCP1_beta	11..527	CDD:239452	369/515 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145945
Domainoid	1	1.000	693	1.000	Domainoid score	I132
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4696
Inparanoid	1	1.050	745	1.000	Inparanoid score	I587
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60896
OrthoDB	1	1.010	-	-		D205390at33208
OrthoFinder	1	1.000	-	-		FOG0004903
OrthoInspector	1	1.000	-	-		oto88642
orthoMCL	1	0.900	-	-		OOG6_101721
Panther	1	1.100	-	-	LDO	PTHR11353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1485
SonicParanoid	1	1.000	-	-		X3458
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800