Protein Alignment CCT2 and CCT2

DIOPT Version :10

• Sequence 1: NP_572524.1
• Gene: CCT2 / 31838
• FlyBaseID: FBgn0030086
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_006422.1
• Gene: CCT2 / 10576
• HGNCID: 1615
• Length: 535
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 380/533 - (71%)
• Similarity: 453/533 - (84%)
• Gaps: 1/533 - (0%)

  Fly     3 MSLNPVRVLKNEAQEEKAEMARLSSFIGAIAIGDLVKSTLGPKGMDKILVATGRNAGHVEVTNDG 67
            :||.||.:.|..|.||:||.|||:|||||||||||||||||||||||||:::||:|. :.|||||
Human     4 LSLAPVNIFKAGADEERAETARLTSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAS-LMVTNDG 67

  Fly    68 ATILRAVGVDNPAAKILVDMSRVQDEEVGDGTTSVTVLASELLREAEKLVEQKLHPQIIVSGWRQ 132
            ||||:.:||||||||:|||||||||:|||||||||||||:|||||||.|:.:|:|||.|::|||:
Human    68 ATILKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIIAGWRE 132

  Fly   133 ATQVALEALTAAAQDNSSSDEKFRNDLLNIARTTLSSKILHQHKDFFANLAVDAVMRLKGSGELK 197
            ||:.|.|||.::|.|:.|.:.|||.||:|||.||||||:|..|||.|..|||:||:||||||.|:
Human   133 ATKAAREALLSSAVDHGSDEVKFRQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLE 197

  Fly   198 SIQIIKKSGGTLGDSFLDEGFLLDKKPGVHQPQRIENARILIANTPMDTDKIKVFGSSIKVDSLA 262
            :|.||||.||:|.||:||||||||||.||:||:|||||:||||||.|||||||:|||.::|||.|
Human   198 AIHIIKKLGGSLADSYLDEGFLLDKKIGVNQPKRIENAKILIANTGMDTDKIKIFGSRVRVDSTA 262

  Fly   263 KIADLEMAEKEKMKEKVDKILKHKCNVFINRQLIYNYPEQLFADARVMSIEHADFDGIERLAYCT 327
            |:|::|.||||||||||::||||..|.|||||||||||||||..|.||:||||||.|:||||..|
Human   263 KVAEIEHAEKEKMKEKVERILKHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAGVERLALVT 327

  Fly   328 GGEIVSTFENPSLVKLGECDVIEQVMIGEDTLLRFSGVKLGEACTIVIRGATQQILDEADRSLHD 392
            ||||.|||::|.|||||.|.:||:||||||.|:.||||.||||||||:|||||||||||:|||||
Human   328 GGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGEACTIVLRGATQQILDEAERSLHD 392

  Fly   393 ALCVLAATVKESRIIFGGGCSEALMATAVLKKAAETPGKEAIAIEAFARALLSLPTAIADNAGYD 457
            ||||||.|||:||.::||||||.|||.||.:.|..||||||:|:|::|:||..|||.||||||||
Human   393 ALCVLAQTVKDSRTVYGGGCSEMLMAHAVTQLANRTPGKEAVAMESYAKALRMLPTIIADNAGYD 457

  Fly   458 SAQLVSELRAGHAQGKQTLGLDMELGKVADVRELGITESFAVKRQVLMSASEAAEMILRVDNIIR 522
            ||.||::|||.|::|..|.||||..|.:.|:..|||||||.||||||:||:||||:||||||||:
Human   458 SADLVAQLRAAHSEGNTTAGLDMREGTIGDMAILGITESFQVKRQVLLSAAEAAEVILRVDNIIK 522

  Fly   523 CAPRRRVPDRGYC 535
            .|||:||||...|
Human   523 AAPRKRVPDHHPC 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT2	NP_572524.1	TCP1_beta	10..527	CDD:239452	370/516 (72%)
CCT2	NP_006422.1	TCP1_beta	11..527	CDD:239452	369/515 (72%)