Protein Alignment CG15365 and lzts2a

DIOPT Version :10

• Sequence 1: NP_001285030.1
• Gene: CG15365 / 31829
• FlyBaseID: FBgn0030077
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_001139078.2
• Gene: lzts2a / 570926
• ZFINID: ZDB-GENE-090313-276
• Length: 709
• Species: Danio rerio
• Alignment Length: 769
• Identity: 164/769 - (21%)
• Similarity: 278/769 - (36%)
• Gaps: 267/769 - (34%)

  Fly   145 SCVGGGGGDGRGGAAEEEAMQSLPATLPQQHQQQQQRRTTPIAGGS---RHQQQQQMG------- 199
            ||.....|..|..:::|:.:.|.| .||.::     :.:..|:.|:   .:...:.:|
Zfish    73 SCFRQQEGTLRSSSSQEQLLNSQP-PLPAKN-----KSSALISAGNGNYGYLSDEPVGDWNDNHV 131

  Fly   200 -------EAEQTSGN----------------------------FLRPIAFKPIPFEPDYRIACQQ 229
                   :.|:.|.|                            .:||.||||:
Zfish   132 STCSPSSDTEEPSDNRGMNGNIGGPPPKLVPVSGRLEKSMEKILIRPTAFKPV------------ 184

  Fly   230 QQQHQQQLQLQQQQQQQQQQQQQQQLQLQHQQQQQHQQQHQHQHQQQHQSLQLPTEGGQAG-GVA 293
                     |.:.:...|....:....|...|                .||.|...|..|| |..
Zfish   185 ---------LPKNRNSVQYLSPRSGGSLSESQ----------------GSLNLLLPGTGAGSGCQ 224

  Fly   294 AERYGY----------------GSTPSLAPLPTASAQKFG---STTDLRHLAARR----RNHRLL 335
            .:|..|                ....||:.|||.|:..:.   |.....|:...|    ..|
Zfish   225 EKRNSYSGGRNARSSQSCTMSDSGRNSLSSLPTYSSTGYSLTQSEVPNGHMETTRSGVGHGH--- 286

  Fly   336 QRCSNEDALTLDLLSTGSHDRPDGASSKSSGTV---------VGSSDLTPSPS---DSGISELEA 388
               ||.|:             ...:||||:|::         .||...:|:|.   :..|.|||.
Zfish   287 ---SNSDS-------------GRSSSSKSTGSLSGRGQPLSDSGSCGRSPAPGEGYEGVIRELEE 335

  Fly   389 ALKDRDSELSYLRQAMEHNEKVIFQVQKDKEVYWEHETQRLRLFYEGQQRECQLKLRKMEQLLGL 453
            .|::||.||..||..::.||..|.||.::|:...|.|.:.||.....:.::.|||.::.:|:|.|
Zfish   336 KLRERDLELQQLRDNLDENEAAICQVYEEKQKRCEQEMEDLRQSCASKMKQVQLKAQRAQQVLQL 400

  Fly   454 QQFQLKQHKLRQSEQVNRLQQQLDLARDSSQGLQQQVDALRHQLEDSEWRVCERNGEIALLKTQL 518
            |.|||:|.|.:..|..::|.|:.:.........:::......:||:::|.||:::|||:|||.||
Zfish   401 QVFQLQQEKKKLQEDFSQLLQEREALEKRCASFEREQTQFGPRLEETKWEVCQKSGEISLLKQQL 465

  Fly   519 KEAHLEINMKDHAIVSLKHSSNRSSSSSNSNSNKSCDTNTSQSQPKQQAKEEQQQQQHPELQQQQ 583
            |:...::..|...||:||                                 .|.::...|||..|
Zfish   466 KDVQADLGQKASEIVALK---------------------------------AQLREARSELQASQ 497

  Fly   584 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLKQQHQPDQQQLQKIITLKDQVIGALTSELAK 648
            .:.|:.....:.:..:.:..:.:.|:::.:.:.|:::                  :|.|..|..:
Zfish   498 ARSQEAHATARTRTLELEVCENELQRRKSEAELLREK------------------MGRLEEESLR 544

  Fly   649 LRKELSDLAIAHEYGEEPCGRYTRLKQQLDNLNEICQKTRKYTTTSASPTAVASPAAQVAPPAPS 713
            |::.:                                         |.||....|:...:...|.
Zfish   545 LKEAM-----------------------------------------AVPTPQTLPSKGQSMSLPL 568

  Fly   714 PAA-----HVATPSCAQELPKLDVLVQRLQLDQGQGTQQTLDTLIEESTTYAEDIAKLRQKLDDF 773
            |.:     |..:|:......:..:|.  .:.|:.:..:|::|.|           ..|||::|..
Zfish   569 PQSRGGIGHGISPAFRDNSSEEQLLA--YESDEAKAQRQSVDVL-----------HGLRQQVDRL 620

  Fly   774 RLNL--------------ELEKRQWSAEKDKVLGYQKQLQAHYIQMYQKLRCLD 813
            |..|              |.|:|.|..|||||:.||||||.:|||||::.|.|:
Zfish   621 RAELMYERRRSEDQLEGFEDERRVWQEEKDKVIRYQKQLQQNYIQMYRRNRDLE 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15365	NP_001285030.1	Fez1	<735..812	CDD:462015	31/90 (34%)
lzts2a	NP_001139078.2	None