Protein Alignment CG15365 and lzts2

DIOPT Version :10

• Sequence 1: NP_001285030.1
• Gene: CG15365 / 31829
• FlyBaseID: FBgn0030077
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_001006721.1
• Gene: lzts2 / 448373
• XenbaseID: XB-GENE-1216151
• Length: 683
• Species: Xenopus tropicalis
• Alignment Length: 744
• Identity: 164/744 - (22%)
• Similarity: 277/744 - (37%)
• Gaps: 266/744 - (35%)

  Fly   158 AAEEEAMQSLPATLP---------------QQHQQQQQRRTTPIAGGSRHQQQQQMGEAEQTSGN 207
            ::::.....||...|               :..:::......||:..|   ..:.:.|....:||
 Frog    83 SSQDPLFNGLPTKKPSTTTSGNNGNYVYVNEDFKEEWHEPRVPISPSS---DAEDIREERALNGN 144

  Fly   208 ----------------------FLRPIAFKPIPFEPDYRIACQQQQQHQQQLQLQQQQQQQQQQQ 250
                                  .::|.||||:           ..::....||...|:.......
 Frog   145 IRGPPPKLIPVSGKLEKNVEKTLIKPTAFKPV-----------VPKKRNSSLQYLVQRNGGPGLS 198

  Fly   251 QQQQLQLQHQQQQQHQQQHQHQHQQQHQSLQLPTEGGQAGGVAAERYGY---------------G 300
            :.|                        .||.|...|..||  ..|::..               |
 Frog   199 ESQ------------------------SSLNLLFNGNAAG--IPEKHNLLSCRNSTHSGTMSDSG 237

  Fly   301 STPSLAPLPTASAQKFGSTTDLRHLAARRRNHRLLQRCSNE-DALTLDL--LSTGSH-------D 355
            .| ||:.|||.|.                       .||:: |.:::.:  ::..:|       |
 Frog   238 RT-SLSSLPTYST-----------------------NCSHQMDPVSVSMGHINLDNHTNINGYSD 278

  Fly   356 R-PDG------------ASSKSSGTVVGSSDLTPSPSDSG-------------ISELEAALKDRD 394
            | |.|            :||||:|::.|..:  || ||||             |.|||..||||:
 Frog   279 RAPRGRTRPTNSDSGRSSSSKSTGSLSGRGN--PS-SDSGSCDRSPILSDEILIRELEEKLKDRE 340

  Fly   395 SELSYLRQAMEHNEKVIFQVQKDKEVYWEHETQRLRLFYEGQQRECQLKLRKMEQLLGLQQFQLK 459
            .||..|::.::.||..|.||.::|:...|.|.:.||.....:.::...|.::::|:|.||.|||:
 Frog   341 MELQQLKENLDENEAAICQVYEEKQKRCEQEMEELRQSCALKMKQAAQKAQRLQQVLQLQIFQLQ 405

  Fly   460 QHKLRQSEQVNRLQQQLDLARDSSQGLQQQVDALRHQLEDSEWRVCERNGEIALLKTQLKEAHLE 524
            |.|.:..|..::|.|:.:|........:::......:||:::|.||:::|||:|||.|||::..|
 Frog   406 QEKKKLQEDFSQLLQERELLEKRCASFEREQTEFGPRLEETKWEVCQKSGEISLLKQQLKDSQAE 470

  Fly   525 INMKDHAIVSLKHSSNRSSSSSNSNSNKSCDTNTSQSQPKQQAKEEQQQQQHPELQQQQQQQQQQ 589
            :..|.:.|:.|:                                 .|.::...:||..::|.|:.
 Frog   471 LAQKSNEILLLR---------------------------------AQVREARSDLQISEEQVQEL 502

  Fly   590 QQQQQQQQQQQQQQQQQQQQQQQQQQQLKQQHQPDQQQLQKIITLKDQVIGALTSELAKLRKELS 654
            |.....:..:.:..:.:.|:::.:.:.|:          :|...|..:|.|...:.:|.||   .
 Frog   503 QDTAHTKTLELEVCENELQRKKNEAELLR----------EKASKLDQEVAGLREAAVANLR---H 554

  Fly   655 DLAIAHEYGEEPCGRYTRLKQQLDNLNEICQKTRKYTTTSASPTAVASPAAQVAPPAPSPAAHVA 719
            .|.:.|| .|:|...|                        .|..|.|
 Frog   555 GLCLCHE-KEDPFLLY------------------------ESDEAKA------------------ 576

  Fly   720 TPSCAQELPKLDVLVQRLQLDQGQGTQQTLDTLIEESTTYAEDIAKLRQKLDDFRLNLELEKRQW 784
                           ||...|..||.||.::.|.|..|:   :..:.:::.|.|    |.|:|.|
 Frog   577 ---------------QRQNADNLQGLQQYVERLREALTS---ERRRYQEQADSF----EDERRIW 619

  Fly   785 SAEKDKVLGYQKQLQAHYIQMYQKLRCLD 813
            ..||:||:.||||||.:||||||:.|.|:
 Frog   620 QEEKEKVIRYQKQLQHNYIQMYQQNRELE 648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15365	NP_001285030.1	Fez1	<735..812	CDD:462015	33/76 (43%)
lzts2	NP_001006721.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	82..107		3/23 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	262..320		17/60 (28%)
		SMC_N	<329..>505	CDD:481474	59/208 (28%)
		Fez1	446..652	CDD:462015	74/314 (24%)