Protein Alignment CG15365 and lzts2b

DIOPT Version :10

• Sequence 1: NP_001285030.1
• Gene: CG15365 / 31829
• FlyBaseID: FBgn0030077
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: XP_017214089.2
• Gene: lzts2b / 100005471
• ZFINID: ZDB-GENE-030131-9587
• Length: 608
• Species: Danio rerio
• Alignment Length: 849
• Identity: 163/849 - (19%)
• Similarity: 300/849 - (35%)
• Gaps: 298/849 - (35%)

  Fly    15 VPPPGTPPVLGGSGCSNLSLPSGKRGHKRS-VSLENNAPLALRSTPSMGQSSLGSPLLQFGQAAP 78
            :.|...|..||..|..:..:|:.....:|: :.:..|   ..:.||..|:.....|  |.|...|
Zfish    11 IDPRLHPAELGAMGAVSSMIPNHITYPERADIEVSTN---FRKGTPDSGRLLWDVP--QAGSRTP 70

  Fly    79 GQ------GHSQGFHTGTLKSRQEQRRLSQKFGSHSNL----DDEGVGIGVGMGMGMGLQMRSKF 133
            |.      |.::||.|.:.              ||.:|    :|..:.:|:
Zfish    71 GNRRRAIVGRAKGFGTRSY--------------SHEDLIRDWNDNHMDVGM-------------- 107

  Fly   134 QNIRQMFELSRSCVGGGGGDGRGGAAEEEAMQSLPATLPQQHQQQQQRRTTPIAGGSRHQQQQQM 198
                      .|.|.|                  |..|            .|::|......||.:
Zfish   108 ----------TSAVDG------------------PPKL------------VPVSGQLERNIQQAI 132

  Fly   199 GEAEQTSGNFLRPIAFKP-IPFEPDYRIACQQQQQHQQQLQLQQQQQQQQQQQQQQQLQLQHQQQ 262
                      :||.|||| ||                        :.:...|....:|.......
Zfish   133 ----------IRPTAFKPVIP------------------------KSRNTAQFLSPRLGTGLSGS 163

  Fly   263 QQHQQQHQHQHQQ-QHQSLQLPTE-GGQAGGVAAERYGYGSTP--SLAPLPTASAQKFGSTTDLR 323
            |.:..:.....:. .|.:|:..:. .|....:.::.:....||  ||..||..:.|...|:
Zfish   164 QGNLSRFSPDAEDVSHATLERRSSYSGARNALFSQSFTMTETPRGSLTNLPAYTQQHSESS---- 224

  Fly   324 HLAARRRNHRLLQRCSNEDALTLDLLSTGSHDRPDGASSKSSGTVVGSSDLT-------PSPS-- 379
                     :|...||:              |....:||||:|::.|...:.       |||.
Zfish   225 ---------KLPGNCSS--------------DSGRSSSSKSTGSLGGRGHMLSDRGSAGPSPPPI 266

  Fly   380 ---DSGISELEAALKDRDSELSYLRQAMEHNEKVIFQVQKDKEVYWEHETQRLRLFYEGQQRECQ 441
               ::.:.:||..|::|:.||..||:.::.||..|.||.::::...|.|.:..|.....:.::..
Zfish   267 EAYEAIVRDLEEKLRERELELQRLRENLDENEAAICQVYEERQKRTELEIEEFRQMCAAKMQKAS 331

  Fly   442 LKLRKMEQLLGLQQFQLKQHKLRQSEQVNRLQQQLDLARDSSQGLQQQVDALRHQLEDSEWRVCE 506
            .|.::.:|:|.:|.||::|.|.:..|::.::.::.....:.....:::...|..:||:::|.||:
Zfish   332 QKAQREQQMLQMQVFQMQQEKKKHQEEMTQILKERQRLEERCSSFEREHTQLGPRLEETKWEVCQ 396

  Fly   507 RNGEIALLKTQLKEAHLEINMKDHAIVSLKHSSNRSSSSSNSNSNKSCDTNTSQSQPKQQAKEEQ 571
            ::|||:|||.|||:...::..:...:|:::                                 .|
Zfish   397 KSGEISLLKQQLKDLQADLAQRVGELVTVR---------------------------------GQ 428

  Fly   572 QQQQHPELQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLKQQHQPDQQQLQKIITLKD 636
            .::...|||..|.|.|:.....:.:..:.:..|.:.|:::.:.:.|:::
Zfish   429 LREVRSELQTSQNQLQEANTTSRTRILELEVCQNELQRRKSENELLREK---------------- 477

  Fly   637 QVIGALTSELAKLRKELSDLAIAHEYGEEPCGRYTRLKQQLDNLNEICQKTRKYTTTSASPTAVA 701
              |..|..:.:::|..|:..|         .|:..||.::.:.|     ||
Zfish   478 --ISHLEEDSSQMRDALNAAA---------SGKEQRLAEETEEL-----KT-------------- 512

  Fly   702 SPAAQVAPPAPSPAAHVATPSCAQELPKLDVLVQRLQLDQGQGTQQTLDTLIEESTTYAEDIAKL 766
                                                       ::|..|.|..|       :|..
Zfish   513 -------------------------------------------SRQQADRLKAE-------LAYE 527

  Fly   767 RQKLDDFRLNLELEKRQWSAEKDKVLGYQKQLQAHYIQMYQKLRCLDSAGAAVG-------QVEA 824
            ||:..|.....|.|::.|..|||||:.||||||.:|:|||::.|.|:.:...:.       |.:.
Zfish   528 RQRFSDQAAAFESERKSWEEEKDKVIRYQKQLQQNYVQMYKRNRDLERSLRELSLELESREQDDD 592

  Fly   825 TSGN 828
            :|||
Zfish   593 SSGN 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15365	NP_001285030.1	Fez1	<735..812	CDD:462015	27/76 (36%)
lzts2b	XP_017214089.2	None