DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32971 and MED22

DIOPT Version :9

Sequence 1:	NP_001137823.1	Gene:	CG32971 / 318271	FlyBaseID:	FBgn0052971	Length:	145	Species:	Drosophila melanogaster
Sequence 2:	NP_598395.1	Gene:	MED22 / 6837	HGNCID:	11477	Length:	200	Species:	Homo sapiens

Alignment Length:	149	Identity:	52/149 - (34%)
Similarity:	87/149 - (58%)	Gaps:	15/149 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 EALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALI 71
            |.||:|:..:|||::.|::.||.|::|........|::..|:.|.:.:||.|||.|.|||||:|:
Human    12 ETLLQSYNKRLKDDIKSIMDNFTEIIKTAKIEDETQVSRATQGEQDNYEMHVRAANIVRAGESLM 76

  Fly    72 KLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKS--- 133
            |||.|:|::.|:.|:.::.|.:|::::.:.....|.|:.||.:..::..:|.|||.|||..|
Human    77 KLVSDLKQFLILNDFPSVNEAIDQRNQQLRTLQEECDRKLITLRDEISIDLYELEEEYYSSSSSL 141

  Fly   134 ------------GGPDLDS 140
                        |..|||:
Human   142 CEANDLPLCEAYGRLDLDT 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32971	NP_001137823.1	Med22	15..117	CDD:283768	36/101 (36%)
MED22	NP_598395.1	Med22	20..124	CDD:283768	36/103 (35%)
MED22	NP_598395.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	166..200
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145389
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55431
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004687
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12434
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.950