Protein Alignment CG10962 and RDH8

DIOPT Version :10

• Sequence 1: NP_788887.1
• Gene: CG10962 / 31824
• FlyBaseID: FBgn0030073
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_056540.3
• Gene: RDH8 / 50700
• HGNCID: 14423
• Length: 311
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 76/285 - (26%)
• Similarity: 113/285 - (39%)
• Gaps: 66/285 - (23%)

  Fly     7 RVAVISGASSGIGAACA---------RLLVAAGLQVVGLARRTDRL--EQLRQSLPAEQRMRFHQ 60
            |..:|||.|||||...|         |..|.|.::.:|.....:..  |.|.|:|...|
Human     6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQ------ 64

  Fly    61 HKCDVSQELQVDTAFEWIEKELGGIDVLINNAGIVLGGQLIDMPTKDINNILQTNLMGSIYCTKL 125
              .||..:..|......|:   |.:|||:||||:.|.|.|..:....:.|:..||..|::...|.
Human    65 --LDVCSDESVAQCLSCIQ---GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKA 124

  Fly   126 AASSMRRRQVAGHLIFVNSTAGVAGYKPDPADESLNAYTPSKFALTAVQEICRQELINQGSKIKT 190
            ....|:||: .||::.::|..|:.|...:      :.|..|||||....|....:|:.  ..|..
Human   125 VLPGMKRRR-QGHIVVISSVMGLQGVIFN------DVYAASKFALEGFFESLAIQLLQ--FNIFI 180

  Fly   191 TSINPGWVATEI---------------VPDETKAKLGEVILQA------------DDVAQAVLYA 228
            :.:.||.|.||.               ...||.....::.|.|            .||.||::..
Human   181 SLVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQNPQDVVQAIVNV 245

  Fly   229 LST--PPHTQVEQI------TLRAV 245
            :|:  ||..:...|      ||:.|
Human   246 ISSTRPPLRRQTNIRYSPLTTLKTV 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10962	NP_788887.1	YdfG	5..245	CDD:443365	75/283 (27%)
RDH8	NP_056540.3	type1_17beta-HSD-like_SDR_c	6..262	CDD:187666	73/275 (27%)