Protein Alignment CG10962 and HSD11B1

DIOPT Version :10

• Sequence 1: NP_788887.1
• Gene: CG10962 / 31824
• FlyBaseID: FBgn0030073
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_005516.1
• Gene: HSD11B1 / 3290
• HGNCID: 5208
• Length: 292
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 58/235 - (24%)
• Similarity: 94/235 - (40%)
• Gaps: 53/235 - (22%)

  Fly     5 QNRVAVISGASSGIGAACARLLVAAGLQVVGLARRTDRLEQLRQSLPAEQRMRFHQHKCDVSQEL 69
            |.:..:::|||.|||...|..|...|..||..||..:.|:::                  ||..|
Human    33 QGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKV------------------VSHCL 79

  Fly    70 QVDTA-----------FEWIE-------KELGGIDVLINNAGIVLGGQLIDMPTKDINNI---LQ 113
            ::..|           ..:.|       |.:||:|:||.|.   :....:::...||:::   ::
Human    80 ELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNH---ITNTSLNLFHDDIHHVRKSME 141

  Fly   114 TNLMGSIYCTKLAASSMRRRQVAGHLIFVNSTAGVAGYKPDPADESLNAYTPSKFALTAVQEICR 178
            .|.:..:..|..|...:  :|..|.::.|:|.||...|      ..:.||:.|||||.......|
Human   142 VNFLSYVVLTVAALPML--KQSNGSIVVVSSLAGKVAY------PMVAAYSASKFALDGFFSSIR 198

  Fly   179 QELINQGSKIKTTSINPGWVATEIVPDETKAKLGEVILQA 218
            :|.......:..|....|.:.||..   .||..|.|.:||
Human   199 KEYSVSRVNVSITLCVLGLIDTETA---MKAVSGIVHMQA 235

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10962	NP_788887.1	YdfG	5..245	CDD:443365	58/235 (25%)
HSD11B1	NP_005516.1	11beta-HSD1_like_SDR_c	32..279	CDD:187593	58/235 (25%)