DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32819 and Tekt5

DIOPT Version :9

Sequence 1:	NP_728444.1	Gene:	CG32819 / 318227	FlyBaseID:	FBgn0052819	Length:	601	Species:	Drosophila melanogaster
Sequence 2:	NP_001277930.1	Gene:	Tekt5 / 70426	MGIID:	1917676	Length:	557	Species:	Mus musculus

Alignment Length:	485	Identity:	175/485 - (36%)
Similarity:	279/485 - (57%)	Gaps:	32/485 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 QAGAPPCMEPVMGPSIPPRVGAAYETP---TKHPWRPAMAYELIQVKHMPEQPVTNQLTKQCFLP 174
            ||..|...|||:.....|     :..|   ..:.|||::.:::...:.:||         :|
Mouse    22 QALPPAGQEPVVQECYQP-----FHLPGYRYLNAWRPSVFHKIATSQTIPE---------EC--- 69

  Fly   175 KGMKTDGMIFPNLVTGFDRNPQHAARAALYTRYTSNEWYNNNMTKYSESNMNRNLSERMRNDAVR 239
            .|::....|.|:|            |:||:.|||..:|..:|..:...:..:|..:.|:..|::|
Mouse    70 SGIRRPPTILPSL------------RSALFCRYTPRDWDRSNDLQIRNAEASRLWASRLTGDSLR 122

  Fly   240 LMRETDEKATSGQRDAGRRLGERITDLTFWRNELNAELEKLIAEMSDINELQRQCGKALLDLEIP 304
            :|::.|:.....|....|.||:|::||.||::||..||::|:.|.|.::.|:|:...|..::..|
Mouse   123 IMQDKDQLIHQMQEGTSRNLGQRLSDLGFWKSELCYELDRLLTENSSMDTLKRRLECAAEEVNCP 187

  Fly   305 LHIAQECLFHRESRQGTEKVHDIVEKALLVEINNLRNSRDRLGGLHEKISKQALDCRGAQHLLED 369
            |.:|.|||::||.|.|.:.|||.|||.|:.|::.|:..:|::..|.::|..|..|.|.|||.||.
Mouse   188 LQVALECLYNREKRIGIDLVHDNVEKNLIREVDLLKCCQDQMRKLAKRIDFQIRDNRDAQHSLER 252

  Fly   370 DVSHKESSLGIDSMCHQLNNHSRGITYYGGIEKFDPSVSTQESWAQASSEHVRRSQAERAKLSQL 434
            |:..|.|:..||..|..|.:.|..|:::.|:||||.:||..|:||:.|::::|.:|..||...:|
Mouse   253 DIEDKSSAQYIDENCFNLRSTSDSISFFHGVEKFDGTVSIPETWAKFSNDNIRHAQNMRANSIRL 317

  Fly   435 RSDAQSVVNSVATTVWDFWSNTNNAFDRRSQEMAEAKNRVQLHLQKVQQELFDMEKHLFLLQKAI 499
            |.:|:.:..:::..:|..::|||.||:.|..|..:.||::|..|.|:.||:|..|..:.||::||
Mouse   318 REEAEHLFETLSDQMWKQFTNTNLAFNARISEETDVKNKLQTQLAKILQEIFQAENTIMLLERAI 382

  Fly   500 QDKSGPLKVAQTRLEARSHREGVELCKDHAQDRLVQEVQDIQGAVETLHHKLMEAEATHQGLLKT 564
            ..|..|||:|||.|..|:.|..||||:|..|.|||.||..|...::||..:|.|.:.|.|.|:.|
Mouse   383 VAKEYPLKMAQTMLACRTRRPNVELCRDVPQFRLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMT 447

  Fly   565 RCTLEVDLRNKVNALFIDREKCMSLRRSFP 594
            :..||.:|..|.|.|.||::||||:|:|||
Mouse   448 KSRLEHELAIKANTLCIDKDKCMSMRKSFP 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32819	NP_728444.1	Tektin	212..591	CDD:281184	147/378 (39%)
Tekt5	NP_001277930.1	Tektin	95..474	CDD:281184	147/378 (39%)
Tekt5	NP_001277930.1	6 X 6 AA approximate tandem repeats of C-[GSK]-G-[GSPH]-A-[SLP]. /evidence=ECO:0000305	507..541
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849274
Domainoid	1	1.000	324	1.000	Domainoid score	I1193
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	337	1.000	Inparanoid score	I2370
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG59762
OrthoDB	1	1.010	-	-		D264325at33208
OrthoFinder	1	1.000	-	-		FOG0000711
OrthoInspector	1	1.000	-	-		otm43153
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19960
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3619
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.010