Protein Alignment HIP and CNS1

DIOPT Version :10

• Sequence 1: NP_570074.3
• Gene: HIP / 318211
• FlyBaseID: FBgn0260484
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_009713.1
• Gene: CNS1 / 852452
• SGDID: S000000359
• Length: 385
• Species: Saccharomyces cerevisiae
• Alignment Length: 259
• Identity: 60/259 - (23%)
• Similarity: 92/259 - (35%)
• Gaps: 69/259 - (26%)

  Fly    43 GGTVPPGQFNGGSAGGKCPFGGVAGAKANEPANAPEDSEDEKSLSD----------------PES 91
            ||...|.::..|               ..:|...|:.||.:...||                .|:
Yeast     8 GGYTKPQKYVPG---------------PGDPELPPQLSEFKDKTSDEILKEMNRMPFFMTKLDET 57

  Fly    92 D------VELDMEGVIEADSDPAQPMGNYSKKATEEEVEQASELRAQAASAYGQQKFDEAIALYT 150
            |      |||:....:..:.:|.:...|:.|        |.:||       |..::|.:|..||:
Yeast    58 DGAGGENVELEALKALAYEGEPHEIAENFKK--------QGNEL-------YKAKRFKDARELYS 107

  Fly   151 K--AIELSPG--NALFHAKRGQAFLKLKKPNACIRDCDVALELNSDLAAGYKFRGRARRLLGDFE 211
            |  |:|....  |...:|.|....|:||....||.||..||.:|......|....:|...|...|
Yeast   108 KGLAVECEDKSINESLYANRAACELELKNYRRCIEDCSKALTINPKNVKCYYRTSKAFFQLNKLE 172

  Fly   212 LAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRLKQERRQAERKIKERQRDQRRARKEQEK 275
            .|......|            .:.:.|..|.|.......:|::.|.|.|| ::.||.|::.:.|
Yeast   173 EAKSAATFA------------NQRIDPENKSILNMLSVIDRKEQELKAKE-EKQQREAQERENK 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIP	NP_570074.3	Hip_N	10..47	CDD:271228	2/3 (67%)
		TPR repeat	126..154	CDD:276809	9/29 (31%)
		NlpI	<139..269	CDD:443815	36/133 (27%)
		TPR repeat	159..189	CDD:276809	12/29 (41%)
		TPR repeat	194..222	CDD:276809	6/27 (22%)
		STI1	299..336	CDD:128966
CNS1	NP_009713.1	3a0801s09	68..>218	CDD:273380	43/177 (24%)
		TPR repeat	83..111	CDD:276809	11/42 (26%)
		TPR repeat	120..150	CDD:276809	12/29 (41%)
		CTWD_TTC4	221..374	CDD:439175	1/3 (33%)