DRSC/TRiP Functional Genomics Resources

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Protein Alignment HIP and HIP1

DIOPT Version :10

Sequence 1:NP_570074.3 Gene:HIP / 318211 FlyBaseID:FBgn0260484 Length:377 Species:Drosophila melanogaster
Sequence 2:NP_567663.1 Gene:HIP1 / 828363 AraportID:AT4G22670 Length:441 Species:Arabidopsis thaliana


Alignment Length:449 Identity:141/449 - (31%)
Similarity:204/449 - (45%) Gaps:128/449 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 MQTGDLKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVPPGQFNGGSAGGKCPFGGVAGAK 69
            |.:..|.:||.|||....:|:.|..|.|.|.:|::|..|..:|.|.....              |
plant     1 MDSTKLSELKVFIDQCKSDPSLLTTPSLSFFRDYLESLGAKIPTGVHEED--------------K 51

  Fly    70 ANEPAN----------------APEDSEDEKSLSDPESDVELDMEGVIEADSDPAQPMGNYSKKA 118
            ..:|.:                .|:..|:|:.....||||||:.: .:|.|:||.|.||:.|.:.
plant    52 DTKPRSFVVEESDDDMDETEEVKPKVEEEEEEDEIVESDVELEGD-TVEPDNDPPQKMGDSSVEV 115

  Fly   119 TEEEVEQASELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDC 183
            |:|..|.|.|.:.:|..|..:..|||||...|:||.|:|.:|:.:..|...::|||||||.|||.
plant   116 TDENREAAQEAKGKAMEALSEGNFDEAIEHLTRAITLNPTSAIMYGNRASVYIKLKKPNAAIRDA 180

  Fly   184 DVALELNSDLAAGYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRL 248
            :.|||:|.|.|.|||.||.||.:||::..||.||..|..:|:|||....||:|.|||.|:|:||.
plant   181 NAALEINPDSAKGYKSRGMARAMLGEWAEAAKDLHLASTIDYDEEISAVLKKVEPNAHKLEEHRR 245

  Fly   249 KQERRQAERKIKERQRDQRRARKE---------QEKHNASS------------------------ 280
            |.:|.:.||:.|:.:||:.|.|.|         :|:.::||                        
plant   246 KYDRLRKEREDKKAERDRLRRRAEAQAAYDKAKKEEQSSSSRPSGGGFPGGMPGGFPGGMPGGFP 310

  Fly   281 -----------------GGSSGEF-----------------------------------SGGNPG 293
                             ||..|.|                                   .||.||
plant   311 GGMGGMPGGFPGGMGGMGGMPGGFPGGMGGGMPAGMGGGMPGMGGGMPAGMGGGGMPGAGGGMPG 375

  Fly   294 NGNM------------SDILGAMSDPEVSAAIQDILSNPGNITKYASNPKIYNLIKKIV 340
            .|.|            .:::.|.|||||.||:||::.||.|:.|:.:|||:..:|.|::
plant   376 GGGMPGGMDFSKILNDPELMTAFSDPEVMAALQDVMKNPANLAKHQANPKVAPVIAKMM 434

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HIPNP_570074.3 Hip_N 10..47 CDD:271228 14/36 (39%)
TPR repeat 126..154 CDD:276809 11/27 (41%)
NlpI <139..269 CDD:443815 63/129 (49%)
TPR repeat 159..189 CDD:276809 14/29 (48%)
TPR repeat 194..222 CDD:276809 15/27 (56%)
STI1 299..336 CDD:128966 17/36 (47%)
HIP1NP_567663.1 Hip_N 3..43 CDD:271228 14/39 (36%)
TPR 117..282 CDD:440225 73/164 (45%)
TPR repeat 123..151 CDD:276809 11/27 (41%)
TPR repeat 156..186 CDD:276809 14/29 (48%)
TPR repeat 191..217 CDD:276809 14/25 (56%)
STI1 385..435 CDD:436075 19/50 (38%)

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