Protein Alignment HIP and St13

DIOPT Version :10

• Sequence 1: NP_570074.3
• Gene: HIP / 318211
• FlyBaseID: FBgn0260484
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_112384.1
• Gene: St13 / 81800
• RGDID: 621312
• Length: 368
• Species: Rattus norvegicus
• Alignment Length: 388
• Identity: 151/388 - (38%)
• Similarity: 213/388 - (54%)
• Gaps: 65/388 - (16%)

  Fly     5 MQTGDLKKLKYFIDFALENPTFLNMPQLQFVKDFVEKFGGTVPPGQFNGGSAGGKCPFGGVAGAK 69
            |....:.:|:.|:....::|:.|:..:::|::::||..||.|||                 |..|
  Rat     1 MDPRKVSELRAFVKMCRQDPSVLHTEEMRFLREWVESMGGKVPP-----------------ATHK 48

  Fly    70 ANEPANAPEDSEDE--------KSLSDPESDVELDMEGVIEADSDPAQPMGNYSKKATEEEVEQA 126
            |....|..|:..|:        :..|..|||:|:|.|||||||:|..|.||:.:.:.||..:::|
  Rat    49 AKSEENTKEEKRDKTTEDNIKTEEPSSEESDLEIDNEGVIEADTDAPQEMGDENAEITEAMMDEA 113

  Fly   127 SELRAQAASAYGQQKFDEAIALYTKAIELSPGNALFHAKRGQAFLKLKKPNACIRDCDVALELNS 191
            :|.:..|..|....:..:||.|:|.||:|:|..|:.:|||...|:||:||||.|||||.|:|:|.
  Rat   114 NEKKGAAIDALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKLQKPNAAIRDCDRAIEINP 178

  Fly   192 DLAAGYKFRGRARRLLGDFELAAHDLRQACKLDFDEETDEWLKEVTPNAKKIEQHRLKQERRQAE 256
            |.|..||:||:|.||||.:|.||.||..|||||:||:....|:||.|.|:||.:||.|.||::.|
  Rat   179 DSAQPYKWRGKAHRLLGHWEEAARDLALACKLDYDEDASAMLREVQPRAQKIAEHRRKYERKREE 243

  Fly   257 RKIKERQRDQRRARKEQEKHNASS------------------GGSSGEFSGGNPGNGN------- 296
            |:||||....::||:|.||.....                  ||..|.|.||.||.|.
  Rat   244 REIKERIERVKKAREEHEKAQREEEARRQSGSQFGSFPGGFPGGMPGNFPGGMPGMGGAMPGMAG 308

  Fly   297 -------MSD--ILGAMSDPEVSAAIQDILSNPGNITKYASNPKIYNLIKKIVPGGDVGAAFG 350
                   :||  :|.||.||||..|.||:..||.|::||.:|||:.|||.|:      .|.||
  Rat   309 MPGLNEILSDPEVLAAMQDPEVMVAFQDVAQNPSNMSKYQNNPKVMNLISKL------SAKFG 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HIP	NP_570074.3	Hip_N	10..47	CDD:271228	9/36 (25%)
		TPR repeat	126..154	CDD:276809	9/27 (33%)
		NlpI	<139..269	CDD:443815	68/129 (53%)
		TPR repeat	159..189	CDD:276809	17/29 (59%)
		TPR repeat	194..222	CDD:276809	16/27 (59%)
		STI1	299..336	CDD:128966	20/38 (53%)
St13	NP_112384.1	Hip_N	3..43	CDD:271228	9/39 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..81		15/59 (25%)
		TPR 1	113..146		12/32 (38%)
		TPR repeat	113..141	CDD:276809	9/27 (33%)
		NlpI	<127..221	CDD:443815	50/93 (54%)
		TPR repeat	146..176	CDD:276809	17/29 (59%)
		TPR 2	147..180		19/32 (59%)
		TPR 3	181..214		20/32 (63%)
		TPR repeat	181..209	CDD:276809	16/27 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..299		12/42 (29%)
		STI1	318..357	CDD:128966	20/38 (53%)