DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32751 and Nit1

DIOPT Version :9

Sequence 1:	NP_001284927.1	Gene:	CG32751 / 318189	FlyBaseID:	FBgn0052751	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_036179.1	Gene:	Nit1 / 27045	MGIID:	1350916	Length:	323	Species:	Mus musculus

Alignment Length:	227	Identity:	47/227 - (20%)
Similarity:	79/227 - (34%)	Gaps:	72/227 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 ESTLNSAGSTTFVPNPEDQINPCLSDPNATYYEEFLVTLSC----------AARNASKYIVINLT 126
            |..|.:....|..||.::....|     |...:|.....:|          .|||.::.::::
Mouse    41 ELPLVAVCQVTSTPNKQENFKTC-----AELVQEAARLGACLAFLPEAFDFIARNPAETLLLS-- 98

  Fly   127 EKQKCEDIPED--------TRPCA---------------SNGLNVFNTNVVFDRQGVVVSRYRKV 168
                 |.:..|        .|.|.               .....::|.:|:.:.:|.||:.|||.
Mouse    99 -----EPLNGDLLGQYSQLARECGIWLSLGGFHERGQDWEQNQKIYNCHVLLNSKGSVVASYRKT 158

  Fly   169 HL-------YGEPKNSTFLPELSTFE----TDFGVTFGHFICFDILFYTPAHQL-IVEQGITDFV 221
            ||       .|..:.|.:.....|.|    |..| ..|..||:|:.|  |...| :.:.|.....
Mouse   159 HLCDVEIPGQGPMRESNYTKPGGTLEPPVKTPAG-KVGLAICYDMRF--PELSLKLAQAGAEILT 220

  Fly   222 YPAMWFSQLPFLTVNG------IFSSKAVQIQ 247
            ||:      .|.:|.|      :..::|::.|
Mouse   221 YPS------AFGSVTGPAHWEVLLRARAIESQ 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32751	NP_001284927.1	biotinidase_like	33..329	CDD:143591	47/227 (21%)
CG32751	NP_001284927.1	Vanin_C	324..503	CDD:408788
Nit1	NP_036179.1	nit	44..311	CDD:143596	46/224 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900