DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rbm13 and mak16

DIOPT Version :9

Sequence 1:	NP_001285026.1	Gene:	Rbm13 / 31818	FlyBaseID:	FBgn0030067	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_775346.2	Gene:	mak16 / 192312	ZFINID:	ZDB-GENE-020419-35	Length:	305	Species:	Danio rerio

Alignment Length:	336	Identity:	168/336 - (50%)
Similarity:	233/336 - (69%)	Gaps:	41/336 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQHDDVVWSII-NKSFCSHKVKTDTRTFCRHEYNLTGLCTRRTCPLANSQYATVREEKGIIYLFI 64
            ||||||:|.:| ||||||:||||.|:.|||:|||:||||.|.:||||||||||:|||||..:|::
Zfish     1 MQHDDVIWDLIGNKSFCSYKVKTKTQQFCRNEYNITGLCNRSSCPLANSQYATIREEKGQCFLYM 65

  Fly    65 KTAERAHMPSKLWERIKLSRNFEKAIEQINENLVFWPKYMIAKNKQRFLKITQYLIRMRRLKLRR 129
            |..|||..||::||::||.||:.||:|||:|||::||:::..|.|||..||||||||:|:|.|:|
Zfish    66 KVIERAAFPSRMWEKVKLDRNYAKALEQIDENLIYWPRFIRHKCKQRLTKITQYLIRIRKLTLKR 130

  Fly   130 QKLIVPLSTKIERREARREEKALVAAKIDNHIEKALMDRLKNGTYRDIYNFSQTAFNKALEAERV 194
            |:.:||||.|:||||.|||||||:||:::|.|||.|:||||.|||.|||||...||:||:|.:..
Zfish   131 QRKLVPLSRKVERREKRREEKALIAAQLENAIEKELLDRLKQGTYGDIYNFPINAFDKAMEKQDE 195

  Fly   195 DEDDEEELDDEDENEEQLEREMEVDGDDSREAEEVQRSLLDEEFVEADTDDEEEDDDDDDDDDED 259
            :.:.|||.::|:|:||:         ..:||      .:.::||.|:|..|.||.::..|..||
Zfish   196 ESESEEEEEEEEEDEEE---------SGTRE------FIAEDEFEESDLSDFEELNNLKDSSDE- 244

  Fly   260 DYDSDSGKREEVEVGSDFEESDEDDDADADDIEETKVPAKKTASKAKKDKKSP-AGNSRRSRSKP 323
                        ||.:: |||.|:.:.:::: ||.|       ||||...|:| .|.||:.|:
Zfish   245 ------------EVNNE-EESSEESEEESEE-EEVK-------SKAKSKGKAPLKGPSRKKRA-- 286

  Fly   324 KLQLEYEYEVE 334
            .:::|||.|.|
Zfish   287 YVEIEYEQETE 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rbm13	NP_001285026.1	PLN00040	1..225	CDD:215038	132/224 (59%)
		Ribosomal_L28e	6..115	CDD:280030	67/109 (61%)
		Mak16	139..241	CDD:282698	47/101 (47%)
mak16	NP_775346.2	MAK16	2..297	CDD:227458	166/333 (50%)
		Ribosomal_L28e	6..116	CDD:280030	67/109 (61%)
		Mak16	152..234	CDD:282698	40/96 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577423
Domainoid	1	1.000	164	1.000	Domainoid score	I3903
eggNOG	1	0.900	-	-		E1_COG5129
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	309	1.000	Inparanoid score	I2593
OMA	1	1.010	-	-		QHG54003
OrthoDB	1	1.010	-	-		D1394336at2759
OrthoFinder	1	1.000	-	-		FOG0004909
OrthoInspector	1	1.000	-	-		oto39864
orthoMCL	1	0.900	-	-		OOG6_102084
Panther	1	1.100	-	-	LDO	PTHR23405
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R678
SonicParanoid	1	1.000	-	-		X3461
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800