Protein Alignment: Moe and nf2

• Sequence 1: NP_727290.1
• Gene: Moe
• FlyBaseID: FBgn0011661
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_012820654.1
• Gene: nf2
• XenbaseID: XB-GENE-984959
• Length: 594
• Species: Xenopus tropicalis
• Alignment Length: 671
• Identity: 271/672 (40%)
• Similarity: 383/672 (57%)
• Gaps: 118/672 (18%)

  Fly    13 RYGGVSVKR---KTLNVRVTTMDAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGD 74
            |....|:||   ||..||:.|||||:||..:....||.|||.|.:|:||||.|||||||| .|..
 Frog     8 RMNFTSLKRKQPKTFIVRIITMDAEMEFNCEMKWKGKDLFDLVCRTLGLRETWFFGLQYT-VKDT 71

  Fly    75 STWIKLYKKPESPAIKTIKYLKRVKKYVDKKTADSNGVNHLETSEEDDDADDMTGSMPFSTWVMN 139
            ..|:|:.||                                                     |::
 Frog    72 IAWLKMDKK-----------------------------------------------------VLD 83

  Fly   140 QDVKKENPLQFRFRAKFYPEDVAEELIQDITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQA 204
            .||.||.|:.|.|.||||||:|.|||:||||..||:||||..||.::||||||.|||||||||||
 Frog    84 HDVPKEEPVTFHFLAKFYPENVEEELVQDITQHLFFLQVKKQILEEKIYCPPEASVLLASYAVQA 148

  Fly   205 RHGDHNKTTHTAGFLANDRLLPQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQD 269
            ::||::.:.|..||||.:.|||:|||:.::|:.:.||:.|..|:.|||...|::|.|||||||||
 Frog   149 KYGDYDPSVHKRGFLAEEELLPKRVINLYQMTPEMWEERITAWYAEHRGRTRDEAEMEYLKIAQD 213

  Fly   270 LEMYGVNYFEIRNKKGTDLWLGVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDK 334
            .||||||||.|||||||:|.||||||||:||:.::|||||..|||:||||||:|:|:|.|||:||
 Frog   214 TEMYGVNYFLIRNKKGTELLLGVDALGLHIYDLENRLTPKTSFPWNEIRNISYSDKEFTIKPLDK 278

  Fly   335 KAPDFMFFAPRVRINKRILALCMGNHELYMRRRKPDTIDVQQMKAQAREEKNAKQQEREKLQLAL 399
            |...|.|.:.::|:||.||.||:|||:|:|||||.|:::||||||||||||..||.||::|....
 Frog   279 KIDVFKFNSSKLRVNKLILQLCIGNHDLFMRRRKADSLEVQQMKAQAREEKARKQMERQRLAREK 343

  Fly   400 AARERAEKKQQEYEDRLKQMQEDMERSQRDLLEAQDMIRRL-------EEQLKQLQAAKDELELR 457
            ..||.||:.:.|.|.||.|::|:.:.:...|:.:::....|       ||:.|.|.....|.|..
 Frog   344 QLREEAERARDELERRLLQLKEEAQMANDALMRSEETADLLAEKAQITEEEAKLLAQKAAEAEQE 408

  Fly   458 QKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQMEVQRIQDEVNAKDEETKRLQDEVEDA----- 517
            .:.::|...|.||       ||..:|:::|..:|...::.:|...:.:|.::|:.::::|
 Frog   409 MQRIKATAIRNEE-------EKRLMEQKVMETEMLAIKMAEESERRVKEAEQLKQDLQEARDSER 466

  Fly   518 RRKQVIA--------AEAAAALLAASTTPQHHHVAEDENENEEELTNGDAGGDVSRDL-----DT 569
            |.||.:.        .:||.|..::||.|.               |:..:...:|..|     ||
 Frog   467 RAKQKLLEISSKTSYMQAAGAASSSSTVPP---------------TDVPSFSMLSDSLPYDFKDT 516

  Fly   570 D------EHIKDPIEDRRTLAERNERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKY 628
            |      |..|:.:|    ..|::..|.:||..||.::...:.:.:|:|.|.:| ||   ...|.
 Frog   517 DMKRLSMEIEKEKVE----YMEKSRHLQEQLNELKTEIESLKLKERESAMDIMH-EN---AGSKQ 573

  Fly   629 KTLREIRKGNTKRRVDQFENM 649
            .|::::...:|:.||..||.:
 Frog   574 NTIKKLTLQSTQCRVAFFEEL 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Moe	NP_727290.1	B41	26..278	CDD:214604	119/252 (47%)
		FERM_N	28..83	CDD:286467	30/55 (55%)
		FERM_M	163..278	CDD:278785	71/115 (62%)
		FERM_C_ERM	272..368	CDD:270015	65/96 (68%)
		GBP_C	<375..497	CDD:303769	43/129 (33%)
		ERM	403..649	CDD:279153	67/277 (24%)
		coiled coil	464..477	CDD:293879	3/13 (23%)
		coiled coil	486..497	CDD:293879	2/11 (18%)
nf2	XP_012820654.1	B41	24..222	CDD:214604	119/252 (47%)
		FERM_N	30..86	CDD:286467	31/110 (28%)
		FERM_M	107..222	CDD:278785	71/115 (62%)
		FERM_C_ERM	216..312	CDD:270015	65/96 (68%)
		ATP-synt_B	316..>417	CDD:304375	36/101 (36%)
		ERM	347..594	CDD:279153	67/277 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D281811at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910