DRSC/TRiP Functional Genomics Resources

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Protein Alignment: Moe and INAVA

Sequence 1:NP_727290.1 Gene:Moe FlyBaseID:FBgn0011661 Length:649 Species:Drosophila melanogaster
Sequence 2:NP_060735.4 Gene:INAVA HGNCID:25599 Length:663 Species:Homo sapiens

Alignment Length:170 Identity:44/171 (26%)
Similarity:72/171 (42%) Gaps:36/171 (21%)


  Fly   407 KKQQEYEDRLKQMQEDMER---SQRDL---LEAQDMIRRLEEQLK---QLQAA----------KD 452
            |:|:..|.||:...|::.|   .:.:|   |.|:..::..|:..|   ::.||          :|
Human   121 KQQRALEARLEACLEELRRLCLREAELTGTLPAEYPLKPGEKAPKVRRRIGAAYKLDDWALHRED 185

  Fly   453 ELELRQKELQAMLQRLEEAKNMEAVEKLKLEEEIMAKQMEVQRIQDEVNAKDEETKRLQD----E 513
            .|...:::|...||..|.|:      :|.|||. :::|...||....:    :|.|:||:    .
Human   186 PLSSLERQLALQLQITEAAR------RLCLEEN-LSRQARRQRKHSML----QEEKKLQELQRCL 239

  Fly   514 VEDARRKQVIAAEAAAALLAASTTPQHHHVAEDENENEEE 553
            ||  ||:......|||..|....:........|....|||
Human   240 VE--RRRNSEPPPAAALPLGRELSASDDSSLSDGLLLEEE 277

Known Domains:


GeneSequenceDomainRegion External IDIdentity
MoeNP_727290.1 B41 26..278 CDD:214604
FERM_N 28..83 CDD:286467
FERM_M 163..278 CDD:278785
FERM_C_ERM 272..368 CDD:270015
GBP_C <375..497 CDD:303769 28/109 (26%)
ERM 403..649 CDD:279153 44/171 (26%)
coiled coil 464..477 CDD:293879 4/13 (31%)
coiled coil 486..497 CDD:293879 3/11 (27%)
INAVANP_060735.4 DUF3338 87..215 CDD:314652 25/101 (25%)
Nuclear localization signal (NLS) 1. {ECO:0000269|PubMed:28436939} 164..170 1/6 (17%)
Nuclear localization signal (NLS) 2. {ECO:0000269|PubMed:28436939} 332..338
Nuclear localization signal (NLS) 3. {ECO:0000269|PubMed:28436939} 422..428
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG3529
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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