Protein Alignment: Moe and Frmd4b

• Sequence 1: NP_727290.1
• Gene: Moe
• FlyBaseID: FBgn0011661
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: XP_001077268.4
• Gene: Frmd4b
• RGDID: 620172
• Length: 1035
• Species: Rattus norvegicus
• Alignment Length: 700
• Identity: 145/700 (21%)
• Similarity: 268/700 (38%)
• Gaps: 201/700 (29%)

  Fly    32 DAELEFAIQSTTTGKQLFDQVVKTIGLREVWFFGLQYTDSKGDSTWIKLYKKPESPAIKTIKYLK 96
            |..||..:|.....::|.|.|.....|:|..:||:.:.|..|...|::|
  Rat    68 DRRLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDTGQENWLQL---------------- 116

  Fly    97 RVKKYVDKKTADSNGVNHLETSEEDDDADDMTGSMPFSTWVMNQDVKKENPLQFRFRAKFYPEDV 161
                       |...:.|               .:|          ||..|....|..:||.|.:
  Rat   117 -----------DHRVLEH---------------DLP----------KKPGPAVLHFAVRFYIESI 145

  Fly   162 AEELIQD-ITLRLFYLQVKNAILTDEIYCPPETSVLLASYAVQARHGDHNKTTHTAGFLANDRLL 225
            :  .::| .|:.||:|..|..:...:|....||...||:..:|...||:....:....|....:.
  Rat   146 S--FLKDKNTVELFFLNAKACVHKGQIEVDSETIFKLAALVLQESKGDYTSDENARKDLKTLPVF 208

  Fly   226 PQRVIDQHKMSKDEWEQSIMTWWQEHRSMLREDAMMEYLKIAQDLEMYGVNYFEIRNKKGTDLWL 290
            |.:.:.:|. |....|..::..:.:.:.:.|..|:::|:||.:.|..|||:|:.:::|:|...||
  Rat   209 PTKTLQEHP-SLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWL 272

  Fly   291 GVDALGLNIYEQDDRLTPKIGFPWSEIRNISFSEKKFIIKPIDKKAPDFMFFAPRVRINKR---- 351
            |:...|:..|:..|::.|:..|.|.::.|:.|.||||.::..|.:         |:.:::|
  Rat   273 GISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPR---------RISVSRRTFGQ 328

  Fly   352 -----------------ILALCMGNHELYMRR----------RKPDTIDVQ-------------- 375
                             |..:.:..|:.|:.|          |..|.|.:.
  Rat   329 SGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTETGTQRVSKLVT 393

  Fly   376 -QMKAQ-------------AREEKNAKQQEREKLQLALAARER--AEKKQQEYEDRLKQMQEDME 424
             :.|:|             :::.:..::|:|||: |.|..:|:  .||..::.|:..|....:.|
  Rat   394 LEAKSQFIMASNGSLISSGSQDSEGMEEQKREKI-LELKKKEKLLQEKLLKKVEELKKICLREAE 457

  Fly   425 RSQR-------DLLEAQDMIRR-------LEEQLKQLQAAKDELELRQKELQAMLQRLEEAKNME 475
            .:.|       ::.|....:||       |::   .|...:::..|::.|...::|:    |.:|
  Rat   458 LTGRMPKEYPLNIGEKPPQVRRRVGTTFKLDD---NLLPTEEDPALQELESNFLIQQ----KLVE 515

  Fly   476 AVEKLKLEEEIMAKQMEVQRIQDEVNAKDEETKRLQDEVEDARRKQVIAAEAAAALLAASTTPQH 540
            |.:||..|.: :.|.::.:|.||..:|    .|||| |:|::..:..|......:..||...|:
  Rat   516 AAKKLASEPD-LCKTVKKKRKQDYTDA----VKRLQ-EIENSINEYRIRCGKKPSQKAAVVPPE- 573

  Fly   541 HHVAEDENENEEELTNGDAGGDVSRDLDTDEHIKDPIEDRRTLAERN------------------ 587
             .:...|:.:..:.|..|                || .|..|||.:.
  Rat   574 -DIIPSESSSLSDTTTYD----------------DP-NDSFTLAGQRPSSVPHSPRILPPKSLGI 620

  Fly   588 ERLHDQLKALKQDLAQSRDETKETANDKIHRENVRQGRDKYKTLREIRKG 637
            ||:|.:..::.:....:|..          ||.:......||||....:|
  Rat   621 ERIHFRKSSINEQFVDTRQS----------REMLSTHSSPYKTLERRPQG 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Moe	NP_727290.1	B41	26..278	CDD:214604	54/247 (22%)
		FERM_N	28..83	CDD:286467	15/51 (29%)
		FERM_M	163..278	CDD:278785	29/116 (25%)
		FERM_C_ERM	272..368	CDD:270015	29/127 (23%)
		GBP_C	<375..497	CDD:303769	31/166 (19%)
		ERM	403..649	CDD:279153	56/269 (21%)
		coiled coil	464..477	CDD:293879	4/13 (31%)
		coiled coil	486..497	CDD:293879	2/11 (18%)
Frmd4b	XP_001077268.4	B41	75..260	CDD:214604	51/240 (21%)
		FERM_N	75..124	CDD:286467	14/91 (15%)
		FERM_M	146..260	CDD:278785	29/117 (25%)
		FERM_C_FRMD4A_FRMD4B	256..366	CDD:270012	27/119 (23%)
		DUF3338	401..529	CDD:288652	28/137 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900