Protein Alignment drd and LOC4575988

DIOPT Version :10

• Sequence 1: NP_001033845.1
• Gene: drd / 318102
• FlyBaseID: FBgn0260006
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_001237269.4
• Gene: LOC4575988 / 4575988
• VectorBaseID: AGAMI1_013930
• Length: 696
• Species: Anopheles gambiae
• Alignment Length: 710
• Identity: 199/710 - (28%)
• Similarity: 322/710 - (45%)
• Gaps: 130/710 - (18%)

  Fly   154 CRRQMHQFLNALDNFDLWALKMHDSSGKLNSGILNGNINQPGDFDQCLGIQQRMNQDQDAGQDQD 218
            |.|::::.|.|..|.:.||:.|.|::.|....:..|.....|.:|:|:...:|:
Mosquito    55 CWREVNRTLEAARNQEPWAVAMLDATVKYPEAVELGARYHLGSYDECVPAGERV----------- 108

  Fly   219 GDSIIRGQYCLAYAQPVLPHNSKRLKSFFKLIQSHGPFKSEFNDPGHRVPRYSL-INWGLCVPSG 282
              :.:|.||||  ||..|        ..|:|.||.|   ...|:|.:..   || :.||:|||:.
Mosquito   109 --APVRPQYCL--AQVAL--------DGFRLQQSAG---RNDNEPSNGT---SLTVRWGVCVPAS 155

  Fly   283 CSARDVEYSVAEYLGNQTASTGITFNVRVEPQMCQVRDQRP---WDR---NTTWAVRFFLLVLSV 341
            |||.:....:|...|           ..|...:||.| .||   :||   .|...:..|:|::
Mosquito   156 CSASETARLLAGASG-----------YAVSDAVCQGR-SRPSDGYDRLQIATACVLAVFVLMV-- 206

  Fly   342 AVLSTIYD----RSTKSQPKQNPW-----FTAFSLDKNLRWLFSTSSAPGDIEAVHGIRFLNAIM 397
             |.||:||    ..::..|::.|.     ..|||..:|||.|...|.....:..::||:.|..:.
Mosquito   207 -VFSTLYDGGGGARSECAPEKRPTGAAAVLRAFSAVENLRKLAQLSKDDHGLGCINGIKALAMVF 270

  Fly   398 LIFSHKSMAMFFNPYNNRTAMSES---------LGQPWTVIGRAASLYTDPFLLFSGMLTSYSLF 453
            ::..|..:.|...|..|.....|.         |..|         |..|.|||.||.     ||
Mosquito   271 ILGGHALVFMAGGPLLNPAFFREQSRLLQNAFLLNSP---------LLVDTFLLLSGF-----LF 321

  Fly   454 GRLM------KQQPIRLKNEYISRLMRIVPP-LAALILFCTYVLPLWGSGPQWNLVVGHHADICK 511
            .||:      :|..:.....|:.|.:|:.|. ||.:.|:.|: ||..|.||.|...:......|:
Mosquito   322 ARLLLLELDKRQGRLNFGLLYLFRYVRLTPAYLAVIALYATW-LPRLGDGPLWTERMELEQRRCR 385

  Fly   512 KNWWRNLLFIHNYFGFSEMCLTHTHHLGIDTELFAVAPLLILALWRWPRRGLFALLLL-CTVGT- 574
            ::||.|:|:::||||...:|:..:.:|..||:||.:||:|:..:||:..|  .||||: |..|.
Mosquito   386 QSWWLNVLYVNNYFGTDSVCMFQSWYLATDTQLFLLAPVLLYPMWRYGHR--VALLLVGCATGVS 448

  Fly   575 -AARYYTTIVNQLS-NYIYFGTNIQRLFRTADY---MYSFPPHRSTVYIMGILLGYVLR--KYQN 632
             |..::.|.|.:|. .::.|...:..| :..||   :|.....|:|.|:.|:|:||::.  :.:|
Mosquito   449 IAVPFFITYVRRLDPTFMVFTDEVHDL-QANDYFVNVYGKTHLRATAYLFGLLVGYLVHWMQIKN 512

  Fly   633 ARLSSLQLRLGWLVATVCVLASLLGPAP----MGDINYVYNSTHAAIYAAFAPIAWCLFFSWIVF 693
            .|:...:|...|..||||...::.....    :|..||::|    |:|||.....|.|...|:|.
Mosquito   513 VRIGRRKLAACWAAATVCGCTAMFSLTAFYTGLGTGNYLHN----ALYAALHRFGWSLSNGWLVL 573

  Fly   694 VSHNGYTNKLTKLFAWRGFQVSTKLSYAIYLTQFPV-FFFNVGRRRHIHHYYNFVSIILDTNEFI 757
            ....|:...|.::.:||.|...::|:|..||....| .:.:..||..:     :.||...|.|.|
Mosquito   574 ACVTGHGRTLHRVLSWRAFVPLSRLTYCAYLMNGLVELYLSASRRTPL-----YASIATLTAESI 633

  Fly   758 S----IFLASVALTVLFDAPFQNLKKLLIK--RPTAAKVVKDSKAKAAESQDATTTTLAS 811
            |    .||.::.|.::|::|...|:|:|:.  |||..       ..|..:::..|.:|::
Mosquito   634 SHMTLTFLLALLLCLMFESPIHGLEKILLSRFRPTHG-------GPAGSAREPETNSLST 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drd	NP_001033845.1	NRF	154..292	CDD:466307	40/138 (29%)
		OafA	377..788	CDD:441440	129/446 (29%)
LOC4575988	XP_001237269.4	None