DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stg1 and Cacng7

DIOPT Version :9

Sequence 1:	NP_001027082.1	Gene:	stg1 / 318064	FlyBaseID:	FBgn0064123	Length:	447	Species:	Drosophila melanogaster
Sequence 2:	XP_036009491.1	Gene:	Cacng7 / 81904	MGIID:	1932374	Length:	304	Species:	Mus musculus

Alignment Length:	242	Identity:	73/242 - (30%)
Similarity:	112/242 - (46%)	Gaps:	37/242 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 SGGAGATDPQGGISNMTTVNGGYLWLITPVAASISVAIVIAALAGPQWLFTEE--KLPNANYNGT 264
            ||.||.|.....: .|:..:...|.|::.|..:..:.:|..|::...||:.||  .||.   |.|
Mouse    16 SGSAGPTGRPPPL-RMSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQ---NQT 76

  Fly   265 ANFK-ALDDGAYITKYTKSSLWILCTTLPGLDADSYNCVKIDYFSNEGYQPDPH---DSTAAIPY 325
            ...| ||..|          ||.:|..   ...:...||..:||    .:|:.:   ::|..|..
Mouse    77 TEVKMALHAG----------LWRVCFF---AGREKGRCVASEYF----LEPEINLVTENTENILK 124

  Fly   326 TVTKSCPIFLAAGVFLVISFIVFLIPTCSH---QNNLYYFSAGILFIVSGLVMLIGLIAYISILK 387
            ||..:.| |....:|||  |..|:|....|   |..:..|.:||.||:|||.:::||:.|||.:.
Mouse   125 TVRTATP-FPMVSLFLV--FTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSIN 186

  Fly   388 AEIGSKLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLF 434
            .|:.:  ||.|:.|  .....||.||......|::.|..||::::||
Mouse   187 DEVMN--RPSSSEQ--YFHYRYGWSFAFAASSFLLKEGAGVMSVYLF 229

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stg1	NP_001027082.1	PMP22_Claudin	235..429	CDD:304458	61/202 (30%)
Cacng7	XP_036009491.1	PMP22_Claudin	45..224	CDD:419754	61/205 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834613
Domainoid	1	1.000	59	1.000	Domainoid score	I10601
eggNOG	1	0.900	-	-		E1_28M76
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000345
OrthoInspector	1	1.000	-	-		otm43441
orthoMCL	1	0.900	-	-		OOG6_111421
Panther	1	1.100	-	-	LDO	PTHR12107
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5605
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730