Protein Alignment Ogg1 and OGG1

DIOPT Version :10

• Sequence 1: NP_572499.2
• Gene: Ogg1 / 31806
• FlyBaseID: FBgn0027864
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_058214.1
• Gene: OGG1 / 4968
• HGNCID: 8125
• Length: 424
• Species: Homo sapiens
• Alignment Length: 291
• Identity: 105/291 - (36%)
• Similarity: 159/291 - (54%)
• Gaps: 14/291 - (4%)

  Fly    33 ECDLERTLLGGQSFRWRSICDGNRTKYGGVVFNTYWVLQQEESFITYEAY-GTSSPLA--TKDYS 94
            |..|:..|..|||||||   :.:...:.||:.:..|.|.|.|..:....| |..|..:  |.|..
Human    32 ELRLDLVLPSGQSFRWR---EQSPAHWSGVLADQVWTLTQTEEQLHCTVYRGDKSQASRPTPDEL 93

  Fly    95 SLISDYLRVDFDLKVNQKDWLSKDDNFVKFLSK--PVRLLSQEPFENIFSFLCSQNNNIKRISSM 157
            ..:..|.::|..|......|.|.|.:|.:...|  .||||.|:|.|.:|||:||.||||.||:.|
Human    94 EAVRKYFQLDVTLAQLYHHWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGM 158

  Fly   158 IEWFCATFGTKIGHFNGADAYTFPTINRFHDIPCEDLNAQLRAAKFGYRAKFIAQTLQEI-QKKG 221
            :|..|..||.::...:....:.||::..   :...::.|.||....||||::::.:.:.| :::|
Human   159 VERLCQAFGPRLIQLDDVTYHGFPSLQA---LAGPEVEAHLRKLGLGYRARYVSASARAILEEQG 220

  Fly   222 GQNWFISLKSMPFEKAREELTLLPGIGYKVADCICLMSMGHLESVPVDIHIYRIAQNYYLPHLTG 286
            |..|...|:...:|:|.:.|.:|||:|.|||||||||::...::||||:|::.|||..|..|.|.
Human   221 GLAWLQQLRESSYEEAHKALCILPGVGTKVADCICLMALDKPQAVPVDVHMWHIAQRDYSWHPTT 285

  Fly   287 Q--KNVTKKIYEEVSKHFQKLHGKYAGWAQA 315
            .  |..:.:..:|:...|:.|.|.|||||||
Human   286 SQAKGPSPQTNKELGNFFRSLWGPYAGWAQA 316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ogg1	NP_572499.2	ogg	33..324	CDD:211589	105/291 (36%)
OGG1	NP_058214.1	ogg	11..322	CDD:211589	105/291 (36%)