Protein Alignment CG32376 and PRSS22

DIOPT Version :10

• Sequence 1: NP_729271.1
• Gene: CG32376 / 318002
• FlyBaseID: FBgn0052376
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: XP_054169579.1
• Gene: PRSS22 / 64063
• HGNCID: 14368
• Length: 425
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 81/301 - (26%)
• Similarity: 134/301 - (44%)
• Gaps: 59/301 - (19%)

  Fly    40 PTPNFGNISSNPFINALE-------AQESFPTRIVNGKRIP----C-----------------TE 76
            |.|........|.:..||       |:.|.|..|:|..|||    |                 :|
Human   104 PGPRKCPAGRGPGVERLESLPGHWRARGSSPPAILNAARIPVPPACGKPQQLNRVVGGEDSTDSE 168

  Fly    77 APFQGSLHYEGYFVCGCVIINKIWILTAHHCF---FGPPEKYTVRVGSDQQRRGGQLRHVKKIVA 138
            .|:..|:...|...|...::...|::||.|||   ...|..::|.:|:.|....|.......:..
Human   169 WPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAW 233

  Fly   139 LAAYNDYTMRH----DLAMMKLKSPVYFGKCVRPVKLPSTKTTKFPKKFV-VSGWGITSANAQNV 198
            :..:..|:.:.    |:|:::|:..:.|.:.|.|:.||.......|.... :||||       ::
Human   234 VEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWG-------SI 291

  Fly   199 Q--------RYLRRVQIDYIKRSKCQKMY-KKAGL-KIYKDMICAS--RTNKDSCSGDSGGPLTS 251
            |        :.|:::::..|....|..:| :.||. .|.:||:||.  ...:|:|.|||||||..
Human   292 QDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMC 356

  Fly   252 R----GVLYGIVSWGIGCANKNYPGVYVNCKRYVPWIKKVI 288
            :    .:|.||:|||.|||.:|.||||::...:..|::|::
Human   357 QVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIV 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32376	NP_729271.1	Tryp_SPc	65..284	CDD:214473	71/263 (27%)
PRSS22	XP_054169579.1	Tryp_SPc	158..396	CDD:238113	66/244 (27%)