Protein Alignment CG32376 and Cfd

DIOPT Version :10

• Sequence 1: NP_729271.1
• Gene: CG32376 / 318002
• FlyBaseID: FBgn0052376
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 245
• Identity: 66/245 - (26%)
• Similarity: 108/245 - (44%)
• Gaps: 39/245 - (15%)

  Fly    65 RIVNGKRIPCTEAPFQGSLHYEGYFVCGCVIINKIWILTAHHCFFGPPEKYTVRV--------GS 121
            ||:.|:.......|:..|:...|..|||..::::.|:|:|.||..|..:..:|:|        ..
Mouse    25 RILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHSLSAP 89

  Fly   122 DQQRRGGQLRHVKKIVALAAYNDYTMRHDLAMMKLKSPVYFGKCVRPVKLPSTKTTKFPKKFV-- 184
            :..:|   ...|:.:|........::..||.:.||......|..|||:.|      ::..|.|
Mouse    90 EPYKR---WYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPL------QYEDKEVEP 145

  Fly   185 -----VSGWGITSANAQNVQRYLRRVQIDYIKRSKCQKMYKKAGLKIYKD------MICASRTNK 238
                 |:|||:.: :|......|.::::..:.|:.|       .|:.|.|      |:||....:
Mouse   146 GTLCDVAGWGVVT-HAGRRPDVLHQLRVSIMNRTTC-------NLRTYHDGVVTINMMCAESNRR 202

  Fly   239 DSCSGDSGGPLTSRGVLYGIVSWGIG-CANKNYPGVYVNCKRYVPWIKKV 287
            |:|.||||.||.....:.|:|:||.. |.|...||||.....|..||:.:
Mouse   203 DTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIENI 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32376	NP_729271.1	Tryp_SPc	65..284	CDD:214473	64/240 (27%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	65/242 (27%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)