Protein Alignment spirit and KLK13

DIOPT Version :10

• Sequence 1: NP_572492.1
• Gene: spirit / 31797
• FlyBaseID: FBgn0030051
• Length: 393
• Species: Drosophila melanogaster
• Sequence 2: NP_056411.1
• Gene: KLK13 / 26085
• HGNCID: 6361
• Length: 277
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 89/292 - (30%)
• Similarity: 124/292 - (42%)
• Gaps: 46/292 - (15%)

  Fly    98 APAVAPIVTRSSQQACNELNKVSKVKEIDEFFVSVVGGMPTRPREFPFMAALGWRSNFDQRIYYR 162
            |..:|.:....|.....|.:||........|   :.||....|...|:.|||..:...      .
Human     5 ALVIASLTLALSGGVSQESSKVLNTNGTSGF---LPGGYTCFPHSQPWQAALLVQGRL------L 60

  Fly   163 CGGALIANNFVLTAAHCADLGGEPPSQVRLGGDNLTLTE-GEDI-SIRRVIIHPDYSASTAY--- 222
            |||.|:...:|||||||...|    .:|.||...|...| ||.: .:...|.||:|..|..:
Human    61 CGGVLVHPKWVLTAAHCLKEG----LKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLNH 121

  Fly   223 -NDIALLELETAAKPELKPTCIWT------QKEVTNTLVTAIGYGQTSFAGLS---SAQLLKVPL 277
             :||.||||::   |......|.|      .:....|.....|:|.|:...::   :.|...:.|
Human   122 DHDIMLLELQS---PVQLTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQL 183

  Fly   278 KSVSNEECQHHYQKDQLAQGVLGTQMCAGDITGERDTCQGDSGGPLLMQDGLLGYVVGITSLGQG 342
            :  |:|||:..|...     :....:|||...|.:|:|:|||||||:....|    .||.|.|..
Human   184 R--SDEECRQVYPGK-----ITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTL----YGIVSWGDF 237

  Fly   343 CASGP--PSVYTRVSSFVDWIEGIV--WPAQQ 370
            ....|  |.||||||.:|.||...:  :..||
Human   238 PCGQPDRPGVYTRVSRYVLWIRETIRKYETQQ 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spirit	NP_572492.1	CLIP	51..98	CDD:197829	89/292 (30%)
		Tryp_SPc	132..364	CDD:238113	80/248 (32%)
KLK13	NP_056411.1	Tryp_SPc	38..261	CDD:238113	80/246 (33%)