DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32260 and f7i

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	NP_775335.1	Gene:	f7i / 282671	ZFINID:	ZDB-GENE-021206-10	Length:	443	Species:	Danio rerio

Alignment Length:	305	Identity:	79/305 - (25%)
Similarity:	128/305 - (41%)	Gaps:	79/305 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   295 VSPSFYPPPPPPPPNNAPRESATCGISGATSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFL 359
            ||...||....|...|            .:.|:.:||:...:|..||...:.|..|:       :
Zfish   165 VSQVDYPCGKIPVQKN------------TSQNQFLGGIHCPRGHCPWQVLIDYNGES-------V 210

  Fly   360 CGGSLIHSRYVITSAHCINP----MLTLVRLGAHDL------SQPAESGAMDLRIRRTVVHEHFD 414
            |||:|:...::||:|||::.    .|..| .|.|||      .:|.|..|:       .:|.::|
Zfish   211 CGGALLEGPWLITAAHCVHQKDTRFLKAV-TGEHDLDVLDGSEEPYEVSAV-------FIHPNYD 267

  Fly   415 LNSISNDIALIELNVVGALPGNISPICLPE---------AAKFMQQDFVGMNPFVAGWG--AVKH 468
            ..::.:|:||:.|.|.........|||||.         ||:|..         ::|||  ...|
Zfish   268 PETLDSDLALLRLRVPVQRSLYAVPICLPTPQLARSELWAARFHT---------LSGWGTRTAGH 323

  Fly   469 --------QGVTSQVLRDAQVPIVSRHSCEQSYKSIFQFVQFSDKVLCAGSSSVD--ACQGDSGG 523
                    :|..|..|:...||::....|..:..:...|        |||.:..|  :|:|..|.
Zfish   324 NLRREKGLKGPASGTLQRLAVPLLPAAQCGNANTTANMF--------CAGYTEGDHASCRGHDGS 380

  Fly   524 PLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVYTRVASYVPWI 568
            ||:....|.:    :|.|:||:|..|..|.:..:||:|.:::.|:
Zfish   381 PLVTRYGETS----FLTGVVSWGRGCGPPGYYWIYTKVENFLIWM 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	71/271 (26%)
		Tryp_SPc	328..571	CDD:238113	72/272 (26%)
f7i	NP_775335.1	GLA	20..82	CDD:214503
		EGF_CA	<91..120	CDD:238011
		FXa_inhibition	129..164	CDD:291342
		Tryp_SPc	188..420	CDD:214473	71/267 (27%)
		Tryp_SPc	188..420	CDD:238113	71/267 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910