DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and AgaP_AGAP001246

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	XP_321901.4	Gene:	AgaP_AGAP001246 / 1281921	VectorBaseID:	AGAP001246	Length:	283	Species:	Anopheles gambiae

Alignment Length:	244	Identity:	67/244 - (27%)
Similarity:	118/244 - (48%)	Gaps:	31/244 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   325 SNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCINP-----MLTLV 384
            |.|:|||.|..: ..|::.:|       |::...:||.|:|::::.:::|||.:|     .|||:
Mosquito    53 SGRIVGGTELTE-PLPYLLSL-------RDSGFHICGASIINAKHALSAAHCQSPPSDVNRLTLL 109

  Fly   385 RLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISNDIALIELNVVGALPGNISPICLPEAAKFM 449
               |....:..|:..:..::.....|..|.|.:..:|:|:|.:........|::.|.|......:
Mosquito   110 ---AGITKRTDETNGILFKVANVTTHPDFSLKTYLSDVAIIRIVTSFLDHPNLAAIPLISTTYKL 171

  Fly   450 QQDFVGMNPFVAGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQSYKSIFQFVQFSDKVLCAGSSSV 514
            :...|..   |:|||......:.:..||..::||||..||...::.    |......:|||....
Mosquito   172 RVSSVAS---VSGWGLTAQDSMLAPTLRTVRIPIVSYSSCVNKWRP----VPIVWTAICAGHPGR 229

  Fly   515 DACQGDSGGPLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVYTRVAS 563
            |:|.|||||||:...::        :||||:|.:....::||:||.|.:
Mosquito   230 DSCNGDSGGPLVQDGVQ--------IGLVSWGADRCGSDYPGIYTYVGN 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	66/242 (27%)
		Tryp_SPc	328..571	CDD:238113	65/241 (27%)
AgaP_AGAP001246	XP_321901.4	Tryp_SPc	55..270	CDD:214473	66/240 (28%)
AgaP_AGAP001246	XP_321901.4	Tryp_SPc	56..270	CDD:238113	65/239 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910