DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and AgaP_AGAP010546

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	XP_314515.4	Gene:	AgaP_AGAP010546 / 1275277	VectorBaseID:	AGAP010546	Length:	295	Species:	Anopheles gambiae

Alignment Length:	239	Identity:	67/239 - (28%)
Similarity:	110/239 - (46%)	Gaps:	41/239 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   342 IAALGYFEENNRNALKFLCGGSLIHSRYVITSAHC------INPMLTLVRLGAHDL---SQPAES 397
            |||:|:...:.:  :.:.||||||...:::|:|||      :.|  .:.|:|  ||   |...:.
Mosquito    78 IAAIGWTGADGK--VNWGCGGSLIWENFILTAAHCAANDEDVPP--DVARMG--DLNIYSDDDDE 136

  Fly   398 GAMDLRIRRTVVHEHFDLNSISNDIALIELNVVGALPGNISPIC--LPEAAKFMQQDFVGMNPFV 460
            ....|||.:.:.|:....::...|:||::|.....:...::|.|  |.:..:|.:.       :.
Mosquito   137 FPQQLRIVKVIRHQQHRFSAKYYDVALMQLEKNITVHETVAPACLWLDDEVRFPKL-------YA 194

  Fly   461 AGWGAVKHQGVTSQVLRDAQVPIVSRHSCEQSYKSIFQFVQFSDK---------VLCAGSSSVDA 516
            ||||........:.:|....:..::...|.:.|.|       |::         .||||...:|.
Mosquito   195 AGWGRTGFGEDKTNILLKVDLTPMNNTQCSKFYTS-------SERGLRNGLHAHHLCAGDEKMDT 252

  Fly   517 CQGDSGGPLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVYTR 560
            |.|||||||.:..|.......:|:|:.|||..|.:.| ||||.|
Mosquito   253 CPGDSGGPLHVKLLHNAKMTPFLVGVTSFGKPCGQAN-PGVYAR 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	67/239 (28%)
		Tryp_SPc	328..571	CDD:238113	67/239 (28%)
AgaP_AGAP010546	XP_314515.4	Tryp_SPc	67..295	CDD:214473	66/237 (28%)
AgaP_AGAP010546	XP_314515.4	Tryp_SPc	67..295	CDD:238113	66/237 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910