DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32260 and gzma

DIOPT Version :9

Sequence 1:	NP_728942.1	Gene:	CG32260 / 317943	FlyBaseID:	FBgn0052260	Length:	575	Species:	Drosophila melanogaster
Sequence 2:	XP_012808240.1	Gene:	gzma / 100135014	XenbaseID:	XB-GENE-482759	Length:	267	Species:	Xenopus tropicalis

Alignment Length:	257	Identity:	85/257 - (33%)
Similarity:	132/257 - (51%)	Gaps:	30/257 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 ISGATSNRVVGGMEARKGAYPWIAALGYFEENNRNALKFLCGGSLIHSRYVITSAHCINPMLTLV 384
            |:|.....::.|.||...:.|::|.: |....:       |||:||...:|:|:|||:.....::
Frog    27 INGNICMDIIDGREAASHSRPYMAYI-YSRTGS-------CGGTLIKQNWVLTAAHCVVNNSEVI 83

  Fly   385 RLGAHDLSQPAESGAMDLRIRRTVVHEHFDLNSISNDIALIELNVVGALPGNISPICLPEAAKFM 449
             ||||.: :..|:......:.|.:.|..|:.....:||.|:::.....|...:|.:.||.....:
Frog    84 -LGAHKV-KSRENEQQRFSVARAIPHPCFEWKKKIHDIQLLQIKGAAKLNKFVSVLKLPTTDMDV 146

  Fly   450 QQDFVGMNPFVAGWGAVKHQGVT-SQVLRDAQVPIVSRHSCEQSYKSIFQFVQFSDKVLCAGS-- 511
            :.   |.:...||||..|..|.| |.|||:..|.:|.|.:|.:.||. |: .:.|..:||||:
Frog   147 KP---GSSCSTAGWGVTKPNGKTPSDVLREVNVTVVDRGTCNKIYKK-FK-TEISTNMLCAGAPK 206

  Fly   512 ---SSVDACQGDSGGPLMMPQLEGNVYRFYLLGLVSFGYECARPNFPGVYTRV-ASYVPWIK 569
               ...|||||||||||:.    |..:.    |:||||.:|..|.:||:|||: |.|:.||:
Frog   207 KSDKKYDACQGDSGGPLIC----GKEFS----GIVSFGKKCGDPKYPGIYTRLTARYLQWIR 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32260	NP_728942.1	CLIP	194..244	CDD:288855
		Tryp_SPc	327..568	CDD:214473	81/247 (33%)
		Tryp_SPc	328..571	CDD:238113	83/249 (33%)
gzma	XP_012808240.1	Tryp_SPc	35..262	CDD:238113	83/249 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910