Protein Alignment CG32221 and Fbxl13

DIOPT Version :8

• Sequence 1: NP_730456.2
• Gene: CG32221 / 317924
• FlyBaseID: FBgn0052221
• Length: 432
• Species: Drosophila melanogaster
• Sequence 2: NP_001096825.2
• Gene: Fbxl13 / 100125363
• RGDID: 1642425
• Length: 634
• Species: Rattus norvegicus
• Alignment Length: 428
• Identity: 85/429 (20%)
• Similarity: 158/429 (37%)
• Gaps: 125/429 (29%)

  Fly    10 LDPSSLLFIFKLLSLEDQLHLARCCRIFRDAFLRLHRHDFQDVVD----KDMS----IRTLEDWR 66
            |...:::.||..|:.:|   |..|.::.|.....:.|....:.:|    |:::    :.||:.||
  Rat   245 LPDQAVVQIFVYLTFKD---LVSCSQVNRSWMSMIQRGSLWNSIDFSTVKNIADRCVVTTLQKWR 306

  Fly    67 TFLWLCGSRIGTLESHFDDDHPLQLLPMISRHCY----RLKSISIYNATVARAQPYLLRMSSLEK 127
                                  |.:|.:..|.|.    .|||:|              ...:|::
  Rat   307 ----------------------LNVLRLNFRGCVLRAKTLKSVS--------------HCKNLQE 335

  Fly   128 VHVRNYKSTSKDLIKAIGIHLPRVNSLSL-----------------ESFERKELQEVRQFSEMLE 175
            ::|.:..|.:.:.::.|....|.|..|:|                 .:.:...|...|:|::.
  Rat   336 LNVSDCPSFTDESMRHISEGCPGVLYLNLSNTTITNRTMRLLPRYFHNLQNLSLAYCRKFTDK-- 398

  Fly   176 LGLYDDVTASEFATIVKPMRKLRCLQLRNAKRFLTTSNLRMLATNCRHLEKLTFND----CDADL 236
             ||       ::..:.....||..|.|....: ::....|.:|.:|..:..||.||    .|..:
  Rat   399 -GL-------QYLNLGNGCHKLIYLDLSGCTQ-ISVQGFRNIANSCTGIMHLTINDMPTLTDNCV 454

  Fly   237 LVL----PQFVNLKYLQLYCSEDMKTRLFKALAKSQCSIQLEYLILHRKRWID---EEQAQYISA 294
            .||    |:..::.::.   |..:....||||  |.|.:: :......||..|   :...:....
  Rat   455 KVLVEKCPRISSVVFIG---SPHISDCAFKAL--SACDLK-KIRFEGNKRITDACFKSVDRNYPG 513

  Fly   295 LKCLRWLVCKPRDDLCVHHLAKLSRLECLSIQSAREIGETQL-------------SLLVAN---- 342
            :..:..:.||...|..:..|:.|.:|..|::.:...||:..|             .|.:||
  Rat   514 ISHIYMVDCKGLTDSSLKSLSVLKQLTVLNLTNCVRIGDIGLRQFFDGPASVKLRELNLANCSLL 578

  Fly   343 --------NER---LRYLNICYCLGITDAFVLDTLASL 369
                    :||   |.|||:..|..:|| ..::.:||:
  Rat   579 GDTSVIRLSERCPNLHYLNLRNCEHLTD-LAIEYIASM 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32221	NP_730456.2	leucine-rich repeat	197..223	CDD:275381	6/26 (23%)
		leucine-rich repeat	224..244	CDD:275381	8/28 (29%)
		leucine-rich repeat	245..272	CDD:275381	7/27 (26%)
		leucine-rich repeat	273..297	CDD:275381	3/27 (11%)
		leucine-rich repeat	298..319	CDD:275381	5/21 (24%)
		leucine-rich repeat	320..345	CDD:275381	9/50 (18%)
		leucine-rich repeat	346..372	CDD:275381	9/25 (36%)
Fbxl13	NP_001096825.2	F-box-like	242..288	CDD:289689	10/46 (22%)
		leucine-rich repeat	257..270	CDD:275381	4/16 (25%)
		leucine-rich repeat	282..308	CDD:275381	7/48 (15%)
		AMN1	308..477	CDD:187754	36/197 (18%)
		leucine-rich repeat	309..327	CDD:275381	6/18 (33%)
		leucine-rich repeat	333..358	CDD:275381	5/25 (20%)
		leucine-rich repeat	359..383	CDD:275381	3/24 (13%)
		leucine-rich repeat	384..411	CDD:275381	5/37 (14%)
		leucine-rich repeat	412..437	CDD:275381	6/26 (23%)
		leucine-rich repeat	438..463	CDD:275381	8/25 (32%)
		leucine-rich repeat	464..486	CDD:275381	6/27 (22%)
		AMN1	475..607	CDD:187754	31/136 (23%)
		leucine-rich repeat	488..538	CDD:275381	8/51 (16%)
		leucine-rich repeat	539..566	CDD:275381	5/27 (19%)
		leucine-rich repeat	567..592	CDD:275381	5/25 (20%)
		leucine-rich repeat	593..617	CDD:275381	9/25 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.667	Consistency score
TreeFam	0	0.000	Not matched by this tool.
	1	0.910