Protein Alignment CG32191 and ARSI

DIOPT Version :10

• Sequence 1: NP_730304.2
• Gene: CG32191 / 317903
• FlyBaseID: FBgn0052191
• Length: 564
• Species: Drosophila melanogaster
• Sequence 2: NP_001012301.1
• Gene: ARSI / 340075
• HGNCID: 32521
• Length: 569
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 179/547 - (32%)
• Similarity: 263/547 - (48%)
• Gaps: 92/547 - (16%)

  Fly    21 SAAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLYAPAMCTPSRGALLSGR 85
            :|..:.|:||.|:.||.|:.||.:.|. :..||.:|.||..|..|:..|...:|||||..||:||
Human    41 AAPPQPPHIIFILTDDQGYHDVGYHGS-DIETPTLDRLAAKGVKLENYYIQPICTPSRSQLLTGR 104

  Fly    86 YPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPEYTPTRRGFDYHFG 150
            |.||||.||.:|..::|..|.|:...:|:..:||||||::||||||||.|.|..|||||||...|
Human   105 YQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLG 169

  Fly   151 YWGAYIDYFQRRSKMPVANYS-------LGYDFRRNMELECRDRGVYVTDLLTAEAERLIKDHAD 208
            .....:||:         .|.       .|:|......:.....|.|.|.|....|..::..|:
Human   170 SLTGNVDYY---------TYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHS- 224

  Fly   209 KEQPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSYIKDPNRRKYAAMISKLDQSVGRIITALSST 273
            .::||||.::..|.||     |||:|.|.:.::..:.:..|||||||::.:|::|..|..||...
Human   225 PQRPLFLYVAFQAVHT-----PLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRY 284

  Fly   274 DQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEGGVRVAGAIWSSGLQARGSIFRQPL 338
            ....||::||.||||    |...:.|||:||||:|.|.||||||..|.:.|..|:.:....|..:
Human   285 GFYNNSVIIFSSDNG----GQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALM 345

  Fly   339 YVADWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHVPREILHILD--------------- 388
            ::.||.|||...|.....::..|||.|:||.:|....:|..  ||||.:|
Human   346 HITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRT--EILHNIDPLYNHAQHGSLEGGF 408

  Fly   389 DVWRL---SALQMGQWKYVNGTTASGRYDSVLTYRELDDLDPRDSRYAVTVRNSATSRALSRYDL 450
            .:|..   :|:::|:||.:.|....|           |.:.|         :..||... |.::|
Human   409 GIWNTAVQAAIRVGEWKLLTGDPGYG-----------DWIPP---------QTLATFPG-SWWNL 452

  Fly   451 RRLTQQRISLTRRLAAVRCGDLQRSCNPLLEECLYDILSDPCEQNNLVYSERHSDVLTALRRRVQ 515
            .|:...|.::                      .|::|.:||.|:.:|  :.:..||:..|..|:.
Human   453 ERMASVRQAV----------------------WLFNISADPYEREDL--AGQRPDVVRTLLARLA 493

  Fly   516 ELRASASRPGNRASMPEADPTLHTCAW 542
            |...:|......|..|.|.|..:..||
Human   494 EYNRTAIPVRYPAENPRAHPDFNGGAW 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32191	NP_730304.2	4-S	27..408	CDD:293753	151/405 (37%)
ARSI	NP_001012301.1	4-S	48..478	CDD:293753	165/496 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	510..539		4/11 (36%)