Protein Alignment otu and duo-1

DIOPT Version :9

• Sequence 1: NP_511089.2
• Gene: otu / 31789
• FlyBaseID: FBgn0003023
• Length: 853
• Species: Drosophila melanogaster
• Sequence 2: NP_505931.3
• Gene: duo-1 / 179586
• WormBaseID: WBGene00001110
• Length: 877
• Species: Caenorhabditis elegans
• Alignment Length: 646
• Identity: 117/646 - (18%)
• Similarity: 208/646 - (32%)
• Gaps: 232/646 - (35%)

  Fly     4 QVQRPITSGSRQAPDPY---DQYL----ESRGL-------YRKHTARDASSLFRVI--AEQMYDT 52
            ::..|..| |:::..|.   |.:|    |:|.|       |...|.:..||...::  .||:|
 Worm   240 EILEPAQS-SKRSESPLLSSDVFLRKLHENRQLVNTGNSCYYNSTMQAVSSCNPLVIRCEQLY-- 301

  Fly    53 QMLHYEIRLECVRFMTLKRRIFEKEIPGDFDSYMQDMS--KPKTYGTMTELRAMSCLYRRNVILY 115
            :|:...|.|            |:       ||...|.:  |.|.......|:.:.||...    :
 Worm   302 RMVRDNIEL------------FD-------DSMNNDQADIKRKYIVLQNFLKVVICLGWH----F 343

  Fly   116 EPYNMGTSVVFNR----RYAEN---FRVFFNNENHFDSVYDVEYIERAAICQSIAFKLLYQKLFK 173
            ...|.|.|:...|    :|.:|   ....|||::..|                 |.:.|...:..
 Worm   344 NKRNEGKSIELRRYDLLQYRQNVGKINEEFNNDDQQD-----------------AHEFLLTLIGA 391

  Fly   174 LPDVSFAVEIMLHPHTFNWDRFNVEFDDKGYMVRIHCTDGRVFKLDLPGDTNCILENYKLCNFHS 238
            :.|   |:.:|..         ||:..|.   |.|.....|.||:|        :|...:|...|
 Worm   392 VDD---AMGVMSK---------NVKTIDN---VGITLNPARAFKID--------VETMYVCQGCS 433

  Fly   239 TNGNQSINARKGGRLEIKNQEERKASGSSGHEPNDLL-------PM------CPNRL-ESCVRQL 289
            ..           .|::.::.:...|...|.....|:       |:      |.::: .||.|
 Worm   434 NE-----------ELKVDSRNDLGVSVMDGCSVQKLVSSFVKWSPIEKECSSCKHKISSSCER-- 485

  Fly   290 LDDGISPFP-------------------------------YKVAKSM--------DPYMYRNIEF 315
                ||.||                               :|:..|.        .|.|:.|.|:
 Worm   486 ----ISTFPECLIINLKRYELEGQGPPFSMKKKSCRVEPSFKLDVSSLGNFPPVEHPEMFENKEY 546

  Fly   316 DCWNDMRKE-AKLYNVYINDYNF---KVGAKCKVELPNETEMYTCHVQNISKDKN-YCHVF---- 371
            .....:..| ::|..:..:|.:|   :|..:.......|....:..|:::.|.|. |.::|
 Worm   547 STTEPVNSEDSRLAEITTDDAHFNDSRVSGRLLGGADEEMSQCSVIVEDVKKRKELYFNIFSNEK 611

  Fly   372 -----VERIG-------------KEIVVPYESLH--PLP-------PDE---YRP---WSLPFRY 403
                 ::.:|             :.|..|...::  .||       ||.   ||.   |....:.
 Worm   612 DFDDILDEMGINNGENQKRFHFERHITGPPSKMYQFQLPGATRGITPDGNCFYRAISWWITGVQS 676

  Fly   404 HRQMPRLPLPKYAGKANK--SSKWKKNKLFEMDQYFEH--------SKCDLMPYMPVDNCYQGVH 458
            |..:.|..:.|:. |.|:  ..|:..|:::|  :|.|:        :.|::.....:.|.....:
 Worm   677 HHMIFREAVGKHL-KKNELMFKKYCHNEIYE--KYVENAMRDGVWATTCEIFAMANMLNVEIITY 738

  Fly   459 IQDDEQRDHNDPEQN---------------DQNPTTEQRDREEPQAQKQHQRTKASRVQPQ 504
            :.|.....|: |:.|               ...|||..|.....::..:.:.|..|.:..:
 Worm   739 LGDSGWVPHS-PQNNYPPRKGAIYLKNTNMHYEPTTSLRKNSPERSPMKKENTNGSSMHDE 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
otu	NP_511089.2	OTU	37..>115	CDD:303090	17/81 (21%)
		TUDOR	335..392	CDD:197660	13/91 (14%)
		TAF12	<446..>564	CDD:304643	11/74 (15%)
duo-1	NP_505931.3	Peptidase_C19Q	270..875	CDD:239138	109/615 (18%)
		OTU	657..>743	CDD:303090	18/88 (20%)
		Peptidase_C19	<750..861	CDD:271592	7/49 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910