DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32110 and Gm9839

DIOPT Version :9

Sequence 1:	NP_729837.1	Gene:	CG32110 / 317858	FlyBaseID:	FBgn0052110	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001186885.1	Gene:	Gm9839 / 408192	MGIID:	3641910	Length:	478	Species:	Mus musculus

Alignment Length:	466	Identity:	137/466 - (29%)
Similarity:	224/466 - (48%)	Gaps:	99/466 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KECQDYPMAKTMPVLKQPENFQ----EQEEDVVMAVQEKLK-FFRKLTSNGPAVPTPLKVVE--K 77
            ::|||    .|..|.|.|...|    ::..|:.:.:::..| ..||.....|..|.||::.|  .
Mouse    35 RKCQD----GTKMVFKVPGKAQKMTPQEPPDLELPIEQSSKGQVRKPQGETPNQPKPLELTEGPP 95

  Fly    78 EDI-----------GHK------EIPKVVKKVDRKTKLLQAIPAVF-----------KHSHNRRF 114
            |.:           |||      |..:.:.:.::|.:|||.:..:.           :.||..
Mouse    96 EQVVTGRVPADSGKGHKRPYSAMEENEQIPQKEKKRRLLQNLKLILIKAGKIKGGESEDSHGS-- 158

  Fly   115 RRSLFLRSNYIEQFRRWTDQKNKLNRKRL---NEAHQLCLK--AKHERIAC---EIDRYKKLILK 171
                       |...|..:....:..|..   :|..:.|.:  :..|:..|   |..|...|...
Mouse   159 -----------ETTLRDPEPSTVVALKECLSPDEREKCCFEETSVTEKKGCVKVEGRRGNSLEPG 212

  Fly   172 QSVHVIEDIRISSELIP-------------LTKEHH---DRLMELSK------------YPLQQV 208
            ....:|.|....:.|:|             ...|.|   |:::::::            .|.:::
Mouse   213 TQAQIILDSSRGNSLLPNKMAVLAAQKKPLRDHEKHREMDQILDITEDMEKEIENALGPGPQEEI 277

  Fly   209 IVAKFNLDICGSDIKILTSGGWLNDKIINFYMNLLVERSEKRPGTVPSVYAMSTFFVPRLLQSGF 273
            :.::|.|.|...||:.|.:..||||::|||||||||||:|.:  ..|:::..||||.|:|..||:
Mouse   278 LSSRFKLQITRGDIQTLKNSQWLNDEVINFYMNLLVERNENQ--GYPALHVFSTFFYPKLKHSGY 340

  Fly   274 DGVKRWTRKVDLFSMDLILVPVHQMLVHWCLVIIDLPAKTMLYYNSRGRGDPNLMRALVKYLQME 338
            ..||||||.::||..:|||||:||.| ||.||:|||..:::.|::|.|:...::...:.:|||.|
Mouse   341 SSVKRWTRGINLFEKELILVPIHQRL-HWSLVVIDLRKQSIAYFDSMGQTGKSICETIFQYLQNE 404

  Fly   339 SEDKLGLCLDTSEFR-----IEDAQNVPQQDNMNDCGVFVCMFAEYLTRDAPITFSKKDMKYFRT 398
            |:.:..:.||..|::     ||:   :|.|.|.:|||:|.|.:|:|:.||.|:|||::.|..||.
Mouse   405 SKTRRNIELDPLEWKQYSVTIEE---IPLQMNGSDCGMFTCKYADYIARDQPVTFSQQHMPTFRK 466

  Fly   399 KMVLELTGDQL 409
            :||.|:...||
Mouse   467 RMVWEILHSQL 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32110	NP_729837.1	Peptidase_C48	230..400	CDD:280975	80/174 (46%)
Gm9839	NP_001186885.1	Peptidase_C48	<231..473	CDD:304959	93/247 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1480705at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1601
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.040