Protein Alignment CG32110 and SENP3

DIOPT Version :10

• Sequence 1: NP_729837.1
• Gene: CG32110 / 317858
• FlyBaseID: FBgn0052110
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_056485.2
• Gene: SENP3 / 26168
• HGNCID: 17862
• Length: 574
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 80/275 - (29%)
• Similarity: 141/275 - (51%)
• Gaps: 29/275 - (10%)

  Fly   143 LNEAHQLCLKAKHERIACEIDRYKKLI---LKQSVHVIEDIRISSELIPLTKEHHDRLMELSKYP 204
            |.|.|..|:::..:..   :..|..||   ..:.|..:|||.......|..|....:|::..:..
Human   309 LREEHVTCVQSILDEF---LQTYGSLIPLSTDEVVEKLEDIFQQEFSTPSRKGLVLQLIQSYQRM 370

  Fly   205 LQQVIVAKFNLD-----ICGSDIKILTSGGWLNDKIINFYMNLLVERSEKRPGTVP-SVYAMSTF 263
            ....:|..|.:.     :...|:..|....||||:::|.|.:|:::       ||| .|:..::|
Human   371 PGNAMVRGFRVAYKRHVLTMDDLGTLYGQNWLNDQVMNMYGDLVMD-------TVPEKVHFFNSF 428

  Fly   264 FVPRLLQSGFDGVKRWTRKVDLFSMDLILVPVHQMLVHWCLVIIDLPAKTMLYYNSRGRGDPNLM 328
            |..:|...|:|||||||:.||:|:.:|:|:|:| :.|||.|:.:|:..:|:.|::|:...:....
Human   429 FYDKLRTKGYDGVKRWTKNVDIFNKELLLIPIH-LEVHWSLISVDVRRRTITYFDSQRTLNRRCP 492

  Fly   329 RALVKYLQMESEDKLGLCLDTSEF----RIEDAQNVPQQDNMNDCGVFVCMFAEYLTRDAPITFS 389
            :.:.||||.|:..|     |..:|    :.....||.:|:|.:|||.||..:.::|....|.:|:
Human   493 KHIAKYLQAEAVKK-----DRLDFHQGWKGYFKMNVARQNNDSDCGAFVLQYCKHLALSQPFSFT 552

  Fly   390 KKDMKYFRTKMVLEL 404
            ::||...|.::..||
Human   553 QQDMPKLRRQIYKEL 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32110	NP_729837.1	Peptidase_C48	230..400	CDD:397169	60/174 (34%)
SENP3	NP_056485.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..125
		Nuclear localization signal. /evidence=ECO:0000255	125..128
		Nuclear localization signal. /evidence=ECO:0000255	153..159
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	161..181
		SENP3_5_N	<295..388	CDD:466160	16/81 (20%)
		Protease	386..543		56/169 (33%)
		Peptidase_C48	400..572	CDD:397169	62/181 (34%)