DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32110 and Semp2l2a

DIOPT Version :9

Sequence 1:	NP_729837.1	Gene:	CG32110 / 317858	FlyBaseID:	FBgn0052110	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_694733.3	Gene:	Semp2l2a / 231201	MGIID:	2667157	Length:	502	Species:	Mus musculus

Alignment Length:	246	Identity:	98/246 - (39%)
Similarity:	153/246 - (62%)	Gaps:	21/246 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 ISSELIPLTKEHHDRLME----------------LSKYPLQQVIVAKFNLDICGSDIKILTSGGW 230
            :::|..|:|.:...|.|:                |...|.::::.::|.|.|...||:.|.:|.|
Mouse   259 LAAEKKPITDQGKGRKMDQILDISEDMEKEIENALGPGPQEEILSSRFKLQISRGDIQTLENGQW 323

  Fly   231 LNDKIINFYMNLLVERSEKRPGTVPSVYAMSTFFVPRLLQSGFDGVKRWTRKVDLFSMDLILVPV 295
            |||::|||||||||||:|.:  ..|:::..||||.|:|..||:..||||||.::||..:|||||:
Mouse   324 LNDEVINFYMNLLVERNENQ--GYPALHVFSTFFYPKLKHSGYSSVKRWTRGINLFEKELILVPI 386

  Fly   296 HQMLVHWCLVIIDLPAKTMLYYNSRGRGDPNLMRALVKYLQMESEDKLGLCLDTSEFR--IEDAQ 358
            ||. |||.||:|||..::::|.:|.|:...::...:.:|||.||:.:..:.||..|::  ...::
Mouse   387 HQR-VHWSLVVIDLRKRSIVYLDSMGQTGKSICETIFQYLQNESKTRRNIELDPLEWKQCSVTSE 450

  Fly   359 NVPQQDNMNDCGVFVCMFAEYLTRDAPITFSKKDMKYFRTKMVLELTGDQL 409
            .:|.|.|.:|||||.|.:|:|:.||.|:|||::.|..||.:||.|:...||
Mouse   451 EIPLQLNGSDCGVFTCKYADYIARDQPVTFSQQHMPTFRKRMVWEILHSQL 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32110	NP_729837.1	Peptidase_C48	230..400	CDD:280975	79/171 (46%)
Semp2l2a	NP_694733.3	Peptidase_C48	<279..497	CDD:304959	91/220 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836050
Domainoid	1	1.000	189	1.000	Domainoid score	I3284
eggNOG	1	0.900	-	-		E1_COG5160
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1480705at2759
OrthoFinder	1	1.000	-	-		FOG0000698
OrthoInspector	1	1.000	-	-		mtm8739
orthoMCL	1	0.900	-	-		OOG6_130490
Panther	1	1.100	-	-	O	PTHR12606
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X425
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.710