Protein Alignment CG1440 and BLMH

DIOPT Version :10

• Sequence 1: NP_001285018.1
• Gene: CG1440 / 31776
• FlyBaseID: FBgn0030038
• Length: 551
• Species: Drosophila melanogaster
• Sequence 2: NP_000377.1
• Gene: BLMH / 642
• HGNCID: 1059
• Length: 455
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 257/467 - (55%)
• Similarity: 337/467 - (72%)
• Gaps: 15/467 - (3%)

  Fly    87 ANSGKNSTHRFAETSVITNQLLEKWRKNFYSEPKNLLAQNVCSRVDPFDVCLSRKALETTNHVFN 151
            ::||.||....|        |::|    ..|:|:.:|||||.:..|..|:||.|..::...|||.
Human     2 SSSGLNSEKVAA--------LIQK----LNSDPQFVLAQNVGTTHDLLDICLKRATVQRAQHVFQ 54

  Fly   152 YKVETEGKPVTNQRSSGRCWLFAALNCIRLPFMKNYNLDEFEFSQAFLFYWDKIERCNYFLNNVV 216
            :.|..||||:|||:||||||:|:.||.:||||||..|::||||||::||:|||:|||.:||:..|
Human    55 HAVPQEGKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFV 119

  Fly   217 KTAQRGEKVDGRLVSFLLLDPTSDGGQWDMLVNLITKHGLMPKKCFPESFSCESSLRMNAILKSK 281
            .||||.|..|||||.|||::|.:||||||||||::.|:|::||||||||::.|::.|||.||..|
Human   120 DTAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDILNHK 184

  Fly   282 LREYARNLRVLMEKNPTDEEIACKIQEQMAEIYKVVGICLGIPSETFTWEYYDKSKNYQSIGPVS 346
            :||:...||.|:....|..||:......|.||::||.||||.|.|||||||.||.||||.|||::
Human   185 MREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPIT 249

  Fly   347 SLEFYERYVKPHFNVEDKVCLVTDPRPTSSYDQAYTVDCLGNVVGGRPVLYNNQSVELLLAVVTK 411
            .||||..:|||.||:|||:|||.||||...|::.|||:.|.|:||||..|||||.::.|..:|..
Human   250 PLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLYNNQPIDFLKKMVAA 314

  Fly   412 SLKAGEAVWFGCEVSKRFASKQGIEDVDVHDFKLVFDIDIQTTFSKADRLIYGESAMTHAMVFTA 476
            |:|.||||||||:|.|.|.||.|:.|::::|.:|||.:.:: ..:||:||.:|||.|||||.|||
Human   315 SIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLK-NMNKAERLTFGESLMTHAMTFTA 378

  Fly   477 VSV--DKSGVAQKLRVENSWGEDRGEKGYLVMNADWFREFGFEVVVDKKYVPEDVLRVFDMDPIV 539
            ||.  |:.|...|.|||||||||.|.||||.|..:||.|:.:|||||:|:|||:||.|.:.:||:
Human   379 VSEKDDQDGAFTKWRVENSWGEDHGHKGYLCMTDEWFSEYVYEVVVDRKHVPEEVLAVLEQEPII 443

  Fly   540 LPAWDPMGTLAQ 551
            ||||||||.||:
Human   444 LPAWDPMGALAE 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1440	NP_001285018.1	Peptidase_C1_2	102..547	CDD:397262	248/446 (56%)
BLMH	NP_000377.1	Peptidase_C1_2	5..451	CDD:397262	252/458 (55%)