Protein Alignment CG18262 and Neu2

DIOPT Version :10

• Sequence 1: NP_572453.1
• Gene: CG18262 / 31745
• FlyBaseID: FBgn0030012
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_649316.1
• Gene: Neu2 / 40375
• FlyBaseID: FBgn0037085
• Length: 382
• Species: Drosophila melanogaster
• Alignment Length: 411
• Identity: 96/411 - (23%)
• Similarity: 149/411 - (36%)
• Gaps: 114/411 - (27%)

  Fly    59 SSSLCSNELESDPIAQDVVEVQGNEELHEELAKEASPDLEEEEEEKEEGSKRQHYQRAAAMKNTL 123
            |:::|.:.||....|.|::|.                                 |:|:......|
  Fly    34 SNTICKSCLEDAQNAFDIIET---------------------------------YERSHQFYRFL 65

  Fly   124 VETREDLLDIELDWTGGEQSEHNETHEEEEGESDDDDTKDSNDTKDMLFQCDQCDRAYNTKRSLQ 188
            .:.||            |:||::.:...||.|:.:.|.:|..|..|
  Fly    66 KDVRE------------EESENDGSGCSEEVEAAERDLQDGADDVD------------------- 99

  Fly   189 SHRRLKHSEANGGSLDKSASERNSKKRKGPPKVYKCNEEACNQTFRTERDLRGHRWKHTG---IF 250
                      :|...|.:..:..:|::.|    :.|:.  |.::|:.:.:|:.|...|||   ..
  Fly   100 ----------SGNEPDINECDIKAKEKPG----FSCSH--CPKSFQVKSNLKVHMRSHTGERPFT 148

  Fly   251 CDICGKPFTQSGNMMRHRQRHSGIKPHKCPECDATFYTQKELSSHSICHTGRMPCICEVCGRPCR 315
            |.:|.|.|..|..:..|.:.|:|.:|.:|..|..:|.....|.:|...|..|....|..|.:...
  Fly   149 CSLCPKSFGYSSGLQNHMRTHTGERPFQCSHCPRSFTAGHHLKAHIQMHERRGSLRCPYCQKCFL 213

  Fly   316 DRGVLTAHMRRHTGERPAKCEVCGKAFYSFHDLNVHAVSHTNLRPFVCDVCGSTF---------- 370
            ...:|..|:..||.|...||..|.|:|...|:|.:|...|.. |.|.|..|...|
  Fly   214 TSLILKQHLATHTDETQFKCSQCSKSFQVEHELWMHMRVHQE-RLFTCGHCSKDFALHAYLKRHL 277

  Fly   371 -------QRKKALRVHKLL-HSEQRKYACKLCGKTFAQSGGLNAHMRSH--------DPARVKGA 419
                   |..|| ..||.| ||:..|  |..|.|||.....|:.|::||        .|.:..|:
  Fly   278 SRNARCSQSSKA-SAHKTLGHSKALK--CGKCPKTFTDRSALSTHLKSHTKNKPLLEGPCKSSGS 339

  Fly   420 VKPLPQSVTIEVIEGKSPPTT 440
             ||...:...:..:..|.|.|
  Fly   340 -KPAHSNAQRKPFKCSSCPRT 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	COG5236	<222..>313	CDD:227561	26/93 (28%)
		C2H2 Zn finger	224..246	CDD:275368	5/21 (24%)
		C2H2 Zn finger	251..271	CDD:275368	6/19 (32%)
		zf-H2C2_2	263..288	CDD:463886	7/24 (29%)
		C2H2 Zn finger	279..327	CDD:275368	11/47 (23%)
		zf-H2C2_2	320..342	CDD:463886	9/21 (43%)
		C2H2 Zn finger	335..355	CDD:275368	7/19 (37%)
		C2H2 Zn finger	363..383	CDD:275368	9/37 (24%)
		zf-C2H2	389..411	CDD:395048	7/21 (33%)
		C2H2 Zn finger	391..411	CDD:275368	7/19 (37%)
Neu2	NP_649316.1	zf-AD	1..63	CDD:462262	9/61 (15%)
		COG5048	<119..241	CDD:227381	35/123 (28%)
		C2H2 Zn finger	121..141	CDD:275368	5/21 (24%)
		zf-H2C2_2	133..156	CDD:463886	8/22 (36%)
		C2H2 Zn finger	149..169	CDD:275368	6/19 (32%)
		zf-H2C2_2	162..185	CDD:463886	6/22 (27%)
		C2H2 Zn finger	177..197	CDD:275368	5/19 (26%)
		C2H2 Zn finger	205..225	CDD:275368	4/19 (21%)
		zf-C2H2_8	206..286	CDD:464935	20/80 (25%)
		C2H2 Zn finger	233..253	CDD:275368	7/19 (37%)
		C2H2 Zn finger	260..297	CDD:275368	9/37 (24%)
		C2H2 Zn finger	303..323	CDD:275368	7/19 (37%)
		C2H2 Zn finger	353..373	CDD:275368	3/7 (43%)