Protein Alignment CG18262 and gli1

DIOPT Version :10

• Sequence 1: NP_572453.1
• Gene: CG18262 / 31745
• FlyBaseID: FBgn0030012
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: XP_002939471.1
• Gene: gli1 / 100494064
• XenbaseID: XB-GENE-482644
• Length: 1371
• Species: Xenopus tropicalis
• Alignment Length: 466
• Identity: 104/466 - (22%)
• Similarity: 156/466 - (33%)
• Gaps: 186/466 - (39%)

  Fly     1 MIKVQPPPDVA----------GGYHNLRCGEVLFSAPASYEVSCLLCDQR--------LPLDGYP 47
            ||:..|...||          |.|.:|..|.:  |....|: :| |..||        .||..|.
 Frog   103 MIRTSPNSLVAFINSRCSSASGSYGHLSIGTI--SPSLGYQ-NC-LNHQRPQGGSYGNNPLMPYN 163

  Fly    48 EHFRLKHFTNSS-------SSLCSNELESDPIAQDVVEVQGNEELHEELAKEASPDLEEEEEEKE 105
            .|   .|.::..       ||:...:|:|:|::...::..|::.|                   |
 Frog   164 SH---DHMSSRGVGMLQPRSSIKHCQLKSEPLSSTGLDPIGSKRL-------------------E 206

  Fly   106 EGSKRQHYQRAAAMKNTLVETREDLLDIELDWTGGEQSEHNETHEEEEGESDDDDTKDSNDTKDM 170
            :||:......|:      |.|::.||.: ||                   ..||..||..
 Frog   207 DGSEGDISSPAS------VGTQDPLLGL-LD-------------------GRDDLEKDDG----- 240

  Fly   171 LFQCDQCDRAYNTKRSLQSHRRLKHSEANGGSLDKSASERNSKKRKGPPKVYK--CNEEACNQTF 233
                                   ||.                     |..||:  |:.|:|.:.|
 Frog   241 -----------------------KHE---------------------PETVYETNCHWESCTKEF 261

  Fly   234 RTERDLRGHRWKHTGIFCDICGKPFTQSGNMMRHRQRHSGIKPHKCPECDATFYTQKELSSHSIC 298
            .|:..|..|                      :.:...|.               .:||.    :|
 Frog   262 DTQEHLVHH----------------------INNEHIHG---------------EKKEF----VC 285

  Fly   299 HTGRMPCICEVCGRPCRDRGVLTAHMRRHTGERPAKC--EVCGKAFYSFHDLNVHAVSHTNLRPF 361
            |.  ..|..|:  ||.:.:.:|..||||||||:|.||  |.|.||:....:|..|..|||..:|:
 Frog   286 HW--QDCSREL--RPFKAQYMLVVHMRRHTGEKPHKCTFEGCNKAYSRLENLKTHLRSHTGEKPY 346

  Fly   362 VC--DVCGSTFQRKKALRVHK-LLHSEQRKYACKL--CGKTFAQSGGLNAHMRS-HDP-----AR 415
            ||  :.|...|........|: ..||.::.|.||:  |.|.:.....|..|::: |.|     .:
 Frog   347 VCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVHGPEAHITKK 411

  Fly   416 VKGAVKPLPQS 426
            .:|...|..||
 Frog   412 HRGDGMPRTQS 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	COG5236	<222..>313	CDD:227561	15/92 (16%)
		C2H2 Zn finger	224..246	CDD:275368	7/21 (33%)
		C2H2 Zn finger	251..271	CDD:275368	0/19 (0%)
		zf-H2C2_2	263..288	CDD:463886	1/24 (4%)
		C2H2 Zn finger	279..327	CDD:275368	12/47 (26%)
		zf-H2C2_2	320..342	CDD:463886	15/23 (65%)
		C2H2 Zn finger	335..355	CDD:275368	7/21 (33%)
		C2H2 Zn finger	363..383	CDD:275368	4/22 (18%)
		zf-C2H2	389..411	CDD:395048	7/24 (29%)
		C2H2 Zn finger	391..411	CDD:275368	6/22 (27%)
gli1	XP_002939471.1	SFP1	<312..402	CDD:227516	29/89 (33%)
		C2H2 Zn finger	318..340	CDD:275368	7/21 (33%)
		C2H2 Zn finger	348..371	CDD:275368	4/22 (18%)
		C2H2 Zn finger	379..400	CDD:275368	6/20 (30%)