Protein Alignment alpha-PheRS and Farsa

DIOPT Version :10

• Sequence 1: NP_572448.1
• Gene: alpha-PheRS / 31740
• FlyBaseID: FBgn0030007
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_079924.2
• Gene: Farsa / 66590
• MGIID: 1913840
• Length: 508
• Species: Mus musculus
• Alignment Length: 492
• Identity: 309/492 - (62%)
• Similarity: 379/492 - (77%)
• Gaps: 5/492 - (1%)

  Fly     7 ERILQHLETTDKA-DTLDLAALFAEDHQKIVGSLKSIQAHGELVTAETVTHKSLGLTDEGRAVVE 70
            |.:|:.||..|.. |:.:||.....:||.:||::||:||.||::.||..:.|...||.||..:..
Mouse     8 ELLLRRLEVADGGLDSAELATQLGVEHQAVVGAVKSLQALGEVIEAELRSTKCWELTTEGEEIAR 72

  Fly    71 NGSHEALVYDLVPPEGIAQAALMAAGGANAKVGFSKAMSHGWILVDKSVTP-PLVRRKVDTITDV 134
            .|||||.|:..:|.||:.|:.||..  .:.|||||||||:.||.||||... |.|.|.||:|.|.
Mouse    73 EGSHEARVFRSIPLEGLVQSELMHL--PSGKVGFSKAMSNKWIRVDKSAADGPRVFRVVDSIEDE 135

  Fly   135 VRNQLQQVALGKGDQLPAKEVADFKKRKLLQETTTKSFVLARGPEFATTLTKLETDLTVEMLANG 199
            |:.:||.|..|:.::|..||..:.:|||||.|...|::.:::|..|:|:::|.|.:|:.||:::|
Mouse   136 VQKRLQLVQAGQAEKLAEKERNELRKRKLLTEVILKTYWVSKGKAFSTSVSKQEAELSPEMISSG 200

  Fly   200 LWDQLKFKAYNFDALGAPPTRGHLHPLLKVRTEFRQIFLEMGFSEMPTNNYVESSFWNFDALYQP 264
            .|....||.|||.|.|..|..||||||||||::||||||||||:||||:|::||||||||||:||
Mouse   201 SWRDRPFKPYNFSARGVLPDSGHLHPLLKVRSQFRQIFLEMGFTEMPTDNFIESSFWNFDALFQP 265

  Fly   265 QQHPARDAHDTFFVNHPAKSHKFPQDYLERVKKVHSVGGYGSKGYGYDWKLEEAQKNLLRTHTTA 329
            |||||||.|||||:..||::.:.|..|::|||:.||.|||||:||.|.||||||:||||||||||
Mouse   266 QQHPARDQHDTFFLRDPAEALQLPMGYVQRVKRTHSQGGYGSQGYKYTWKLEEARKNLLRTHTTA 330

  Fly   330 VSARMLYKLANQEGGFKAAKYFSIDKVFRNETLDATHLAEFHQVEGVIADVGLTLGDLIGTLYEF 394
            .|||.||:|| |:..|..|||||||:|||||||||||||||||:||||||.|||||.|:|.|.||
Mouse   331 ASARALYQLA-QKKPFTPAKYFSIDRVFRNETLDATHLAEFHQIEGVIADHGLTLGHLMGVLREF 394

  Fly   395 FRKLGITQLEFKPAYNPYTEPSMEIFCYHPGLAKWIEVGNSGVFRPEMLLPMGLPENVNVIAWGL 459
            |.|||||||.||||||||||||||:|.||.||.||:||||||||||||||||||||||:||||||
Mouse   395 FTKLGITQLRFKPAYNPYTEPSMEVFSYHQGLKKWVEVGNSGVFRPEMLLPMGLPENVSVIAWGL 459

  Fly   460 SLERPTMIKYGINNIRDLVGPKVDLKMVEEGPICRLD 496
            ||||||||||||||||:|||.||:|:||.:.|:||||
Mouse   460 SLERPTMIKYGINNIRELVGHKVNLQMVYDSPVCRLD 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha-PheRS	NP_572448.1	PLN02853	4..496	CDD:215458	307/490 (63%)
Farsa	NP_079924.2	PLN02853	22..497	CDD:215458	304/478 (64%)