Protein Alignment CG2256 and HPCAL1

DIOPT Version :9

• Sequence 1: NP_572437.2
• Gene: CG2256 / 31727
• FlyBaseID: FBgn0029995
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: NP_001245286.1
• Gene: HPCAL1 / 3241
• HGNCID: 5145
• Length: 193
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 52/220 - (23%)
• Similarity: 103/220 - (46%)
• Gaps: 35/220 - (15%)

  Fly   101 MDELSGKVNPKLLDSLRKKTRFTKDELDALCRIYRKLVSNCQYAAKTLASSSSSAAIAKPHAAVE 165
            |.:.:.|:.|::|..||:.|.||..||.   ..|:..:.:|...                |..|:
Human     1 MGKQNSKLRPEVLQDLRENTEFTDHELQ---EWYKGFLKDCPTG----------------HLTVD 46

  Fly   166 GIDRIVFRELLHSTFDIVTEEILMERIFCSWDKAHEGLPLRLEGWLIGLSTFLRGTPAERAAFCF 230
                 .|:::..:.|.........|.:|.::|...:| .:....::|.||...||...::..:.|
Human    47 -----EFKKIYANFFPYGDASKFAEHVFRTFDTNGDG-TIDFREFIIALSVTSRGKLEQKLKWAF 105

  Fly   231 RVYDLNTDGFITKDEMFTLLR------NCLIKQPQDEDPDEGVKDLVEIVLKKFDLDKDGKVSLE 289
            .:|||:.:|:|::.||..:::      :.::|.|:||...|...|.   :.::.|.:.|||:|||
Human   106 SMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDK---IFRQMDTNNDGKLSLE 167

  Fly   290 DFMGTVTAEPLLIEAFGQCLPTDSA 314
            :|:....::|.::... ||.|:.::
Human   168 EFIRGAKSDPSIVRLL-QCDPSSAS 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2256	NP_572437.2	EFh	228..292	CDD:238008	21/69 (30%)
		EF-hand_7	229..292	CDD:290234	21/68 (31%)
HPCAL1	NP_001245286.1	FRQ1	13..179	CDD:227455	46/193 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810