Protein Alignment CG1571 and dic1

DIOPT Version :9

• Sequence 1: NP_572435.1
• Gene: CG1571 / 31725
• FlyBaseID: FBgn0029993
• Length: 651
• Species: Drosophila melanogaster
• Sequence 2: NP_001342791.1
• Gene: dic1 / 5802757
• PomBaseID: SPBC646.17c
• Length: 544
• Species: Schizosaccharomyces pombe
• Alignment Length: 564
• Identity: 113/564 - (20%)
• Similarity: 201/564 - (35%)
• Gaps: 157/564 - (27%)

  Fly    48 EKSTQLSRQMALTVMETENVTLDQHGMYHYEGGWPKEVNFNDEEQTQRHRKKVEREDSWGEQVLS 112
            ::..::.|...|.:...||.| |.....:.||  ||:::   |:|......|:.:..:...|
pombe     6 KREIEIKRAKLLLLKNKENCT-DAVSSSNKEG--PKQIS---EDQLSNFLCKILKPTNLTPQ--- 61

  Fly   113 MIRTTMSVAEQNNTL---------NIYQNF-----FADLPPELGHDIKMRFRARVANVFHDLWLP 163
                |.|:..:::.|         ::||::     .::..|.:...:.:|..::  ::.|....|
pombe    62 ----TYSLESKSSNLVSDCELKISSVYQSYSSTFNVSNHVPSISKTVNIRETSK--HLKHSTKAP 120

  Fly   164 ARQLRS----IEWMPN---------------NSRQFMTQYT-----------------NH----- 187
            ...|.:    |:.:.|               .|.|..|.||                 ||
pombe   121 KCSLPTSALEIDHLNNFLHSSAKILDRALCDQSNQLFTDYTVKKKSKKNKSQLEENGLNHLFTFQ 185

  Fly   188 --------------------------FAK-GERLRPVTDEPFGGTNGF-YVWDVKNPLKPRITYD 224
                                      :|| .|.||         |.|. .||:.:....|.....
pombe   186 DEKITLNSVVNSISYSSFFEELLITSYAKPKEALR---------TRGLAIVWNQRWKNSPESVLK 241

  Fly   225 SKQQVSLAKICPKDENNMVGGTGLGQVCLWGTFKGGLPIR-NCPLEVSHRETTSALCWVHSKSNT 288
            ::.::::.|..|.....:.||...|||.||...:|..|:. ...:...|.|..:.:.::::..:.
pombe   242 ARSEITVCKPSPFHPQLIAGGAYNGQVFLWDLRQGQYPVSFTTIISGGHLEPVTDITYINNPPSN 306

  Fly   289 EFYSGSLDGSIKYWDTRDLKMPMQELLLEPEPQERQSRMDSHG----VTVLEFEYTIP---VRFI 346
            ...:.|.||.:..|:......|.:.:.|       .|::||..    .|.|.|   ||   :.|:
pombe   307 NIVTCSTDGLVHIWEPDMFSRPSETICL-------SSQVDSSSQCIPATCLSF---IPENNMEFL 361

  Fly   347 IGSDMGHVFVGNR------KGMTPMETLLAHYQLFVGPV---RSINRNPFFVKN--FLVTG--DW 398
            :|::.|.:..|.|      |.:.|.......:.:|:..:   .|.::|.|..||  |.:|.  ||
pombe   362 VGAEDGKLQRGYRSDYSETKAVQPSNVSYEGHNVFISGIDVMTSNSQNVFLEKNKDFALTSSFDW 426

  Fly   399 RARIW-------------SEEVKDS---PSTMYFRKNAQILCGAWSTGRCSLFVTGDINGVVDFW 447
            ..|:|             |.::.:.   .|...|...|.:....|.......|.:.|..|.::.|
pombe   427 TVRLWQCSPSRNQHELVPSNDLDEQVIINSCKTFTHKAMVFDVKWCVSEPCCFASVDALGNLNLW 491

  Fly   448 DLLLHHRKPIRS--VDFKVAIADLVFRPEGDLLAIGLKNGDTHI 489
            ||......|:.|  .|.| .:..:.::||...||.|..||:.||
pombe   492 DLQKDVEAPVTSDIPDGK-PLNKIAWQPEKRNLACGGLNGNVHI 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1571	NP_572435.1	WD40	210..462	CDD:295369	62/290 (21%)
		WD40	211..>488	CDD:225201	70/315 (22%)
		WD40 repeat	229..269	CDD:293791	11/40 (28%)
		WD40 repeat	277..325	CDD:293791	6/47 (13%)
		WD40 repeat	332..369	CDD:293791	12/45 (27%)
		WD40 repeat	379..415	CDD:293791	13/58 (22%)
		WD40 repeat	422..447	CDD:293791	4/24 (17%)
dic1	NP_001342791.1	WD40	223..536	CDD:330360	74/323 (23%)
		WD40 repeat	247..289	CDD:293791	11/41 (27%)
		WD40 repeat	294..339	CDD:293791	7/51 (14%)
		WD40 repeat	348..390	CDD:293791	12/44 (27%)
		WD40 repeat	397..453	CDD:293791	12/55 (22%)
		WD40 repeat	466..504	CDD:293791	8/37 (22%)
		WD40 repeat	511..535	CDD:293791	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1587
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770